SCHEMBL8193784

SCHEMBL8193784

O=C(O)c1ccccc1/N=N/c1ccc(O)c2ccccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ IDE P14735 1/20 0.57
▸ MAPT P10636 6/20 0.52
▸ MEN1 O00255 5/20 0.52
▸ KMT2A Q03164 5/20 0.52
▸ NPSR1 Q6W5P4 4/20 0.52
▸ GAA P10253 3/20 0.52
▸ L3MBTL1 Q9Y468 3/20 0.52
▸ HPGD P15428 3/20 0.50
▸ POLB P06746 2/20 0.50
▸ CDC25B P30305 2/20 0.50
▸ THRB P10828 2/20 0.50
▸ ALDH1A1 P00352 2/20 0.50
▸ TDP1 Q9NUW8 2/20 0.50
▸ PSMD14 O00487 1/20 0.50
▸ HSP90AA1 P07900 1/20 0.50
▸ MMP2 P08253 1/20 0.50
▸ MAPK1 P28482 1/20 0.50
▸ LMNA P02545 1/20 0.48
▸ MYC P01106 1/20 0.48
▸ GLO1 Q04760 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8193788 1.00 IDE (0.57) IDEMAPTMEN1KMT2ANPSR1
SCHEMBL21686794 0.84 IDE (0.51) IDEMAPTMEN1KMT2ANPSR1
SCHEMBL27157136 0.82 IDO1 (0.59) IDEMAPTMEN1KMT2ANPSR1
SCHEMBL68504 0.82 IDE (0.71) IDEMAPTMEN1KMT2ANPSR1
SCHEMBL7201502 0.82 IDO1 (0.65) MAPTMEN1KMT2ANPSR1GAA
SCHEMBL68503 0.82 IDE (0.71) IDEMAPTMEN1KMT2ANPSR1
SCHEMBL8180059 0.81 GLO1 (0.68) IDEMAPTMEN1KMT2ANPSR1
SCHEMBL8180055 0.81 GLO1 (0.68) IDEMAPTMEN1KMT2ANPSR1
SCHEMBL3418834 0.80 IDE (0.66) IDEMAPTMEN1KMT2ANPSR1
SCHEMBL1287836 0.80 IDE (0.66) IDEMAPTMEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5612221-A Avidin-binding fluorescing and quenching reagent for use in homogeneous assays DADE CHEMISTRY SYSTEMS INC. (US) 1997-03-18 — — US claimed
US-5536820-A Avidin-binding azo reagents E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-07-16 — — US claimed
US-6030846-A Homogeneous assays using avidin-binding azo reagents DADE BEHRING INC. (US) 2000-02-29 — — US disclosed
US-5612221-A Avidin-binding fluorescing and quenching reagent for use in homogeneous assays DADE CHEMISTRY SYSTEMS INC. (US) 1997-03-18 — — US disclosed
US-5536820-A Avidin-binding azo reagents E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-07-16 — — US disclosed
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