Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14142331 | 0.89 | RXRA (0.30) | RXRARXRB | |
| SCHEMBL29032467 | 0.81 | HTR1A (0.38) | HTR1AHTR7RXRARXRB | |
| SCHEMBL2234118 | 0.80 | PDCD1 (0.32) | HTR1AHTR7 | |
| SCHEMBL29556985 | 0.80 | PDCD1 (0.32) | HTR1AHTR7 | |
| SCHEMBL2235436 | 0.80 | BRD4 (0.32) | — | |
| SCHEMBL2233080 | 0.79 | EDNRB (0.30) | — | |
| Hydrochloric Acid SCHEMBL2231317 | 0.79 | PDCD1 (0.31) | HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL2232394 | 0.79 | BRD4 (0.31) | — | |
| SCHEMBL5837617 | 0.79 | HTR1A (0.38) | HTR1AHTR7RXRARXRB | |
| Hydrochloric Acid SCHEMBL2233740 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136993-A | CONTACTING IN GROUP 4 METAL COMPLEX OR ITS LEWIS BASE ADDUCT WITH METAL COMPLEX, RECOVERING RESULTING PRODUCT | THE DOW CHEMICAL COMPANY (US) | 2000-10-24 | — | — | US | claimed |
| US-6136993-A | CONTACTING IN GROUP 4 METAL COMPLEX OR ITS LEWIS BASE ADDUCT WITH METAL COMPLEX, RECOVERING RESULTING PRODUCT | THE DOW CHEMICAL COMPANY (US) | 2000-10-24 | — | — | US | disclosed |
| US-6084115-A | METAL DIENE-CONTAINING COMPLEXES BY REACTION WITH THE DIVALENT DERIVATIVE OF A BRIDGED BIDENTATE LIGAND; METALLOCENES; RACEMIC ISOMER USED TO PREPARE ISOTACTIC POLYOLEFINS, E.G., CRYSTALLINE POLYPROPYLENE. | THE DOW CHEMICAL COMPANY (US) | 2000-07-04 | — | — | US | disclosed |