Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.32 |
| ▸ | RAMP1 | O60894 | 3/20 | 0.31 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13573774 | 0.92 | REN (0.35) | DDB1CRBNRAMP1CALCRLREN | |
| SCHEMBL8190835 | 0.92 | REN (0.35) | DDB1CRBNRAMP1CALCRLREN | |
| SCHEMBL26047191 | 0.92 | REN (0.35) | DDB1CRBNRAMP1CALCRLREN | |
| SCHEMBL8190821 | 0.92 | ADRB3 (0.30) | SCN9A | |
| SCHEMBL8190248 | 0.91 | DDB1 (0.30) | DDB1CRBN | |
| SCHEMBL12770115 | 0.86 | DDB1 (0.34) | DDB1CRBNSCN9A | |
| SCHEMBL8179857 | 0.85 | DDB1 (0.36) | DDB1CRBNSCN9ARAMP1CALCRL | |
| SCHEMBL13757915 | 0.85 | DDB1 (0.36) | DDB1CRBNSCN9ARAMP1CALCRL | |
| SCHEMBL3375539 | 0.85 | DDB1 (0.36) | DDB1CRBNSCN9ARAMP1CALCRL | |
| SCHEMBL3375346 | 0.85 | DDB1 (0.36) | DDB1CRBNSCN9ARAMP1CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120716-A1 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | PHENOMIX CORPORATION (US) | 2010-05-13 | — | — | US | disclosed |
| US-20100120716-A1 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | PHENOMIX CORPORATION (US) | 2010-05-13 | — | — | US | disclosed |
| WO-2008070733-A2 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | PHENOMIX CORPORATION (US) | 2008-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120716-A1 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | PREP, HPN, PEPD | DDB1 3432/4885CRBN 2577/4885SCN9A 4784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.