Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 5/20 | 0.34 |
| ▸ | RAMP1 | O60894 | 3/20 | 0.34 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8190835 | 1.00 | REN (0.35) | RENNAMPTRAMP1CALCRLBACE1 | |
| SCHEMBL26047191 | 1.00 | REN (0.35) | RENNAMPTRAMP1CALCRLBACE1 | |
| SCHEMBL8194226 | 0.92 | DDB1 (0.36) | RENRAMP1CALCRLBACE1DDB1 | |
| SCHEMBL13336392 | 0.92 | NAMPT (0.33) | RENNAMPTBACE1DRD2EPHX2 | |
| SCHEMBL8180607 | 0.92 | NAMPT (0.33) | RENNAMPTBACE1DRD2EPHX2 | |
| SCHEMBL8192438 | 0.87 | FAP (0.34) | NAMPTADAM10MMP1ERBB2 | |
| SCHEMBL5611990 | 0.85 | RAMP1 (0.34) | RENNAMPTRAMP1CALCRLBACE1 | |
| SCHEMBL8278256 | 0.85 | REN (0.33) | RENNAMPTRAMP1CALCRLBACE1 | |
| SCHEMBL13886148 | 0.85 | REN (0.33) | RENNAMPTRAMP1CALCRLBACE1 | |
| SCHEMBL8182060 | 0.84 | FAP (0.34) | NAMPTADAM10MMP1ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230279406-A1 | INDUCIBLE CONTROL OF GENE EXPRESSION | TRUSTEES OF BOSTON UNIVERSITY (US) | 2023-09-07 | — | — | US | disclosed |
| US-11660288-B2 | Drug-controlled systems and uses thereof | TRUSTEES OF BOSTON UNIVERSITY (US) | 2023-05-30 | — | — | US | disclosed |
| US-11660288-B2 | Drug-controlled systems and uses thereof | TRUSTEES OF BOSTON UNIVERSITY (US) | 2023-05-30 | — | — | US | disclosed |
| US-20230159600-A1 | REGULATED SYNTHETIC GENE EXPRESSION SYSTEMS | TRUSTEES OF BOSTON UNIVERSITY (US) | 2023-05-25 | — | — | US | disclosed |
| US-11572565-B2 | Inducible control of gene expression | TRUSTEES OF BOSTON UNIVERSITY (US) | 2023-02-07 | — | — | US | disclosed |
| US-11530246-B2 | Regulated synthetic gene expression systems | TRUSTEES OF BOSTON UNIVERSITY (US) | 2022-12-20 | — | — | US | disclosed |
| US-20220025381-A1 | INDUCIBLE CONTROL OF GENE EXPRESSION | TRUSTEES OF BOSTON UNIVERSITY (US) | 2022-01-27 | — | — | US | disclosed |
| US-11059864-B2 | Chimeric antigen receptor (CAR) modulation | TRUSTEES OF BOSTON UNIVERSITY (US) | 2021-07-13 | — | — | US | disclosed |
| US-20200377564-A1 | REGULATED SYNTHETIC GENE EXPRESSION SYSTEMS | TRUSTEES OF BOSTON UNIVERSITY (US) | 2020-12-03 | — | — | US | disclosed |
| US-20200308234-A1 | CHIMERIC ANTIGEN RECEPTOR (CAR) MODULATION | TRUSTEES OF BOSTON UNIVERSITY (US) | 2020-10-01 | — | — | US | disclosed |
| WO-2009152051-A1 | SYNTHESIS OF A MACROCYCLIC HCV PROTEASE INHIBITOR | PHENOMIX CORPORATION (US) | 2009-12-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11059864-B2 | Chimeric antigen receptor (CAR) modulation | HAVCR2, CPB1, CTRL | REN 525/4885NAMPT 3678/4885RAMP1 208/4885 |
| US-20230159600-A1 | REGULATED SYNTHETIC GENE EXPRESSION SYSTEMS | SRRT, BPTF, MYCBP | REN 4092/4885NAMPT 4000/4885RAMP1 3580/4885 |
| US-11660288-B2 | Drug-controlled systems and uses thereof | ATF4, MRPL21, SARS1 | REN 3865/4885NAMPT 2807/4885RAMP1 1877/4885 |
| US-11530246-B2 | Regulated synthetic gene expression systems | SRRT, BPTF, MYCBP | REN 4092/4885NAMPT 4000/4885RAMP1 3580/4885 |
| US-20200308234-A1 | CHIMERIC ANTIGEN RECEPTOR (CAR) MODULATION | HAVCR2, CPB1, CTRL | REN 525/4885NAMPT 3678/4885RAMP1 208/4885 |
| US-20200377564-A1 | REGULATED SYNTHETIC GENE EXPRESSION SYSTEMS | SRRT, BPTF, MYCBP | REN 4092/4885NAMPT 4000/4885RAMP1 3580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.