Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.53 |
| ▸ | HTR5A | P47898 | 2/20 | 0.50 |
| ▸ | DRD1 | P21728 | 4/20 | 0.49 |
| ▸ | DRD5 | P21918 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6024361 | 0.90 | NOX1 (0.53) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL5738879 | 0.80 | MAPT (0.48) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL8994250 | 0.80 | PDE3B (0.59) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL30228538 | 0.79 | MAPT (0.53) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL703728 | 0.79 | MAOB (0.58) | MAOAMAOBPDE3BPDE3A | |
| SCHEMBL11534726 | 0.79 | MAPT (0.53) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL29724095 | 0.79 | MAOB (0.58) | MAOAMAOBPDE3BPDE3A | |
| SCHEMBL407439 | 0.77 | NPC1 (0.70) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL6969939 | 0.77 | MAPT (0.62) | KMT2AMEN1MAPTGAAKDM4E | |
| SCHEMBL30105853 | 0.77 | MAPT (0.62) | KMT2AMEN1MAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738262-B1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK AS (DK) | 2000-04-19 | — | — | EP | disclosed |
| US-6043239-A | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND ESTERS THEREOF IN WHICH A SUBSTITUTED ALKYL CHAIN FORMS PART OF THE N-SUBSTITUENT; TREATMENT OF PAINFUL, HYPERALGESIC AND/OR INFLAMMATORY CONDITIONS | NOVO NORDISK A/S (DK) | 2000-03-28 | — | — | US | disclosed |
| EP-0869777-A1 | NOVEL METHOD | NOVO NORDISK A/S (DK) | 1998-10-14 | — | — | EP | disclosed |
| US-5668129-A | ANTIINFLAMMATORY AGENTS, ANALGESICS OR ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 1997-09-16 | — | — | US | disclosed |
| WO-1997022338-A1 | NOVEL METHOD | NOVO NORDISK A/S (DK) | 1997-06-26 | — | — | WO | disclosed |
| US-5595989-A | ANTIINFLAMMATORY AGENTS AND ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 1997-01-21 | — | — | US | disclosed |
| EP-0738262-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1996-10-23 | — | — | EP | disclosed |
| WO-1995018793-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1995-07-13 | — | — | WO | disclosed |
| EP-0108715-A1 | Dibenzazepine carboxamides | CIBA-GEIGY AG (CH) | 1984-05-16 | — | — | EP | disclosed |
| US-3968217-A | ANTIDEPRESSANT | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-07-06 | — | — | US | disclosed |