Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.59 |
| ▸ | SNCA | P37840 | 1/20 | 0.55 |
| ▸ | BCL2 | P10415 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1764375 | 0.87 | PKM (0.65) | PDE3BPDE3AALDH1A1PKMCYP1A2 | |
| SCHEMBL28978962 | 0.81 | PDE3B (0.56) | PDE3BPDE3AALDH1A1PKMCYP1A2 | |
| SCHEMBL3186685 | 0.81 | PDE3B (0.56) | PDE3BPDE3AALDH1A1PKMCYP1A2 | |
| SCHEMBL565913 | 0.80 | DRD2 (0.53) | PDE3BPDE3ASNCABCL2ALDH1A1 | |
| SCHEMBL11534726 | 0.80 | MAPT (0.53) | PDE3BPDE3ASNCAALDH1A1MAPT | |
| SCHEMBL8194403 | 0.80 | KMT2A (0.57) | PDE3BPDE3AMAPTKMT2AMEN1 | |
| SCHEMBL30228538 | 0.80 | MAPT (0.53) | PDE3BPDE3ASNCAALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL2208192 | 0.79 | DRD2 (0.52) | PDE3BPDE3ASNCABCL2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2208190 | 0.79 | DRD2 (0.52) | PDE3BPDE3ASNCABCL2ALDH1A1 | |
| SCHEMBL6986056 | 0.78 | PDE3B (0.46) | PDE3BPDE3ASNCABCL2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542019-B1 | 8-Hydroxy-2H-dibenz(b,f) azepin-2 one dyes | BAYER AG (US) | 1996-08-14 | — | — | EP | disclosed |
| EP-0542019-A1 | 8-Hydroxy-2H-dibenz(b,f) azepin-2 one dyes | Bayer Corporation (US) | 1993-05-19 | — | — | EP | disclosed |
| US-5208326-A | 8-HYDROXY-2H-DIBENZ(B,F)AZEPIN-2-ONE DYES | MILES INC. (US) | 1993-05-04 | — | — | US | disclosed |