Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | CA12 | O43570 | 5/20 | 0.54 |
| ▸ | CA1 | P00915 | 5/20 | 0.54 |
| ▸ | CA2 | P00918 | 5/20 | 0.54 |
| ▸ | CA7 | P43166 | 5/20 | 0.54 |
| ▸ | CA9 | Q16790 | 5/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4111155 | 0.86 | KDM4E (0.59) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL322149 | 0.82 | CA12 (0.69) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL2884559 | 0.81 | CA12 (0.50) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL28451530 | 0.80 | CA12 (0.67) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL2534149 | 0.78 | CA12 (0.65) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL11453172 | 0.77 | HMGCR (0.51) | KDM4ECA9HSP90AA1RAB9AALDH1A1 | |
| SCHEMBL16750520 | 0.77 | KDM4E (0.51) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL2899565 | 0.77 | KDM4E (0.73) | KDM4ERAB9AALDH1A1NPC1TP53 | |
| SCHEMBL2865009 | 0.76 | CA12 (0.51) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL8196776 | 0.76 | KDM4E (0.50) | KDM4ERAB9AALDH1A1NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078724-A2 | IMIDAZOLINDERIVATIVES THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |