Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA7 | P43166 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | XDH | P47989 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26829548 | 0.84 | ATM (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8195367 | 0.81 | KDM4E (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1091896 | 0.80 | MAOA (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2478058 | 0.80 | KDM4E (0.56) | GAAL3MBTL1KDM4ENFKB1NFKB2 | |
| SCHEMBL1109633 | 0.80 | CA12 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL21468462 | 0.79 | KDM4E (0.54) | GAAL3MBTL1KDM4ENFKB1NFKB2 | |
| SCHEMBL4041645 | 0.79 | HTT (0.47) | CA9GAALMNAL3MBTL1KDM4E | |
| SCHEMBL10881982 | 0.78 | MAPT (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1538335 | 0.78 | CA12 (0.63) | CA12CA1CA2CA7CA9 | |
| Hydrochloric Acid SCHEMBL10884801 | 0.77 | MAPT (0.59) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705043-B2 | Substituted aminodicarboxylic acid derivatives having pharmaceutical properties | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-04-27 | — | — | US | disclosed |
| US-20070179139-A1 | Substituted aminodicarboxylic acid derivatives having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2007-08-02 | — | — | US | disclosed |
| US-20040082798-A1 | Novel amino dicarboxylic acid derivatives with pharmaceutical properties | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-04-29 | — | — | US | disclosed |
| EP-1368335-A2 | NOVEL AMINO DICARBOXYLIC ACID DERIVATIVES WITH PHARMACEUTICAL PROPERTIES | Bayer Aktiengesellschaft (DE) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002070510-A2 | AMINO DICARBOXYLIC ACID DERIVATIVES WITH PHARMACEUTICAL PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | disclosed |
| EP-0109815-B1 | IMPROVEMENTS IN AND RELATING TO SUBSTITUTED TETRAHYDRONA PHTHALENES | ELI LILLY AND COMPANY (US) | 1986-05-28 | — | — | EP | disclosed |
| US-4500545-A | HYPOTENSIVE, ANTISECRETORY AGENTS, AND DOPAMINE ANTAGONIST | ELI LILLY AND COMPANY (US) | 1985-02-19 | — | — | US | disclosed |
| EP-0109815-A1 | Improvements in and relating to substituted tetrahydrona phthalenes | ELI LILLY AND COMPANY (US) | 1984-05-30 | — | — | EP | disclosed |
| US-4448990-A | Hydroxyaminotetralincarboxamides | ELI LILLY AND COMPANY (US) | 1984-05-15 | — | — | US | disclosed |
| US-4254056-A | ANTIINFLAMMATORY AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1981-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082798-A1 | Novel amino dicarboxylic acid derivatives with pharmaceutical properties | ABAT, BCAT2, GOT1 | CA12 1423/4885CA1 863/4885CA2 140/4885 |
| US-20070179139-A1 | Substituted aminodicarboxylic acid derivatives having pharmaceutical properties | ACMSD, AADAT, DDC | CA12 1384/4885CA1 1919/4885CA2 341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.