Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SCN2B | O60939 | 2/20 | 0.39 |
| ▸ | SCN1B | Q07699 | 2/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9064537 | 0.87 | CNR2 (0.49) | CNR2NOTUMCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9064654 | 0.86 | CNR2 (0.46) | CNR2NOTUMNPSR1CYP1A2CYP2C9 | |
| SCHEMBL9428110 | 0.85 | CNR2 (0.50) | CNR2NOTUMNPSR1CYP1A2CYP2C9 | |
| SCHEMBL9064743 | 0.84 | CNR2 (0.44) | CNR2NOTUMNPSR1CYP1A2CYP2C9 | |
| SCHEMBL8424239 | 0.84 | CNR2 (0.44) | CNR2NOTUMNPSR1CYP1A2CYP2C9 | |
| SCHEMBL8427987 | 0.84 | NOTUM (0.46) | CNR2NOTUMNPSR1CYP1A2CYP2C9 | |
| SCHEMBL8425725 | 0.83 | CNR2 (0.43) | CNR2NOTUMNPSR1CYP1A2CYP2C9 | |
| SCHEMBL8425428 | 0.83 | CNR2 (0.43) | CNR2NOTUMNPSR1CYP1A2CYP2C9 | |
| SCHEMBL8428409 | 0.82 | CNR2 (0.43) | CNR2NOTUMNPSR1CYP1A2CYP2C9 | |
| SCHEMBL9064734 | 0.82 | CYP2C9 (0.46) | CNR2NOTUMNPSR1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000042032-A1 | SUBSTITUTED 2-IMINO THIAZOLINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |