SCHEMBL8424239

SCHEMBL8424239

Cc1cn(-c2cccc(C(F)(F)F)c2)c(=NC(=O)C(F)F)s1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 5/20 0.44
NOTUM Q6P988 1/20 0.40
SCN2B O60939 2/20 0.39
SCN1B Q07699 2/20 0.39
SCN5A Q14524 2/20 0.39
SCN9A Q15858 2/20 0.39
SCN1A P35498 1/20 0.39
HTT P42858 1/20 0.38
POLB P06746 1/20 0.38
CYP1A2 P05177 3/20 0.37
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
MEN1 O00255 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
KMT2A Q03164 1/20 0.36
NPC1 O15118 1/20 0.36
TNF P01375 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8425725 0.92 CNR2 (0.43) CNR2NOTUMSCN2BSCN1BSCN5A
SCHEMBL8428409 0.91 CNR2 (0.43) CNR2NOTUMSCN2BSCN1BSCN5A
SCHEMBL8425428 0.90 CNR2 (0.43) CNR2NOTUMSCN2BSCN1BSCN5A
SCHEMBL9064537 0.87 CNR2 (0.49) CNR2NOTUMSCN2BSCN1BSCN5A
SCHEMBL8425557 0.86 MAPT (0.40) CNR2NOTUMSCN2BSCN1BSCN5A
SCHEMBL8425465 0.86 CNR2 (0.40) CNR2NOTUMSCN2BSCN1BSCN5A
SCHEMBL9064654 0.86 CNR2 (0.46) CNR2NOTUMSCN2BSCN1BSCN5A
SCHEMBL8424559 0.86 CNR2 (0.40) CNR2NOTUMSCN2BSCN1BSCN5A
SCHEMBL9428110 0.85 CNR2 (0.50) CNR2NOTUMSCN2BSCN1BSCN5A
SCHEMBL8424264 0.85 GABRA2 (0.35) CNR2NOTUMSCN2BSCN1BSCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7089945-A None JP disclosed
JP-5070309-A None JP disclosed
EP-0636616-B1 Process for production of fluoroalkanecarboxamide derivatives SUMITOMO CHEMICAL CO (JP) 1999-10-27 EP disclosed
US-5508415-A HAVING STRONG HERBICIDAL POTENCY, NOTICEABLE SELECTIVITY BETWEEN CROP PLANTS AND WEEDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-16 US disclosed
US-5484933-A Process for production of fluoroalkane carboxamide derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-01-16 US disclosed
US-5426188-A Iminothiazolines, their production and use as herbicides, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-06-20 US disclosed
EP-0531970-B1 Herbicidal composition SUMITOMO CHEMICAL CO (JP) 1995-04-12 EP disclosed
JP-H0789945-A PRODUCTION OF FLUOROALKANECARBOXAMIDE DERIVATIVE SUMITOMO CHEM CO LTD 1995-04-04 JP disclosed
EP-0636616-A1 Process for production of fluoroalkanecarboxamide derivatives SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-02-01 EP disclosed
US-5312798-A 2-Acylimino-3-substituted phenylthiazolines and one or more of the following: triazines, uracils, ureas, dinitroanilines, norflurazon, dimethazone, imazaquin, imazethapyr SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-05-17 US disclosed
US-5244863-A Iminothiazolines, their production and use as herbicides, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-09-14 US disclosed
JP-H0570309-A HERBICIDAL COMPOSITION SUMITOMO CHEM CO LTD 1993-03-23 JP disclosed
EP-0531970-A1 Herbicidal composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-03-17 EP disclosed
JP-H00570309-A 0001-01-01 JP disclosed