Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.64 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.62 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.59 |
| ▸ | MASP2 | O00187 | 1/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.51 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.47 |
| ▸ | CDK1 | P06493 | 2/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.47 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SCN4A | P35499 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4064398 | 0.84 | LTA4H (0.48) | LTA4HSCN10ASCN2AMASP2DYRK1A | |
| Hydrochloric Acid SCHEMBL4298486 | 0.83 | LTA4H (0.47) | LTA4HSCN10ASCN2AMASP2DYRK1A | |
| SCHEMBL16324218 | 0.80 | NPY5R (0.60) | LTA4HSCN10ASCN2AMASP2DYRK1A | |
| SCHEMBL1181922 | 0.80 | SCN2A (0.87) | SCN10ASCN2ACCNB2CDK1CCNB1 | |
| SCHEMBL17269665 | 0.80 | SCN2A (0.61) | SCN10ASCN2ADYRK1ACCNB2CDK1 | |
| SCHEMBL4064403 | 0.79 | SMN1; SMN2 (0.57) | MAPTKMT2ANPC1RAB9AKDM4E | |
| SCHEMBL4053949 | 0.79 | MASP2 (0.70) | LTA4HSCN10ASCN2AMASP2MAPT | |
| SCHEMBL10570411 | 0.79 | SCN2A (0.59) | SCN10ASCN2ADYRK1ACCNB2CDK1 | |
| SCHEMBL25834553 | 0.78 | SCN10A (0.57) | SCN10ASCN2ADYRK1ACCNB2CDK1 | |
| Hydrochloric Acid SCHEMBL4298488 | 0.78 | SMN1; SMN2 (0.56) | MAPTKMT2ANPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000006552-A1 | 4-PHENYL- AND 4,5-DIPHENYLIMIDAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION | SANOFI-SYNTHELABO (FR) | 2000-02-10 | — | — | WO | disclosed |