Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2467062 | 0.89 | SMN1; SMN2 (0.57) | CHRM2SMN1; SMN2HTTCA12CA1 | |
| SCHEMBL3836788 | 0.82 | CALM1 (0.55) | CALM1IGF1RALOX15CA12CA1 | |
| SCHEMBL4254058 | 0.81 | CALM1 (0.72) | CALM1IGF1RALOX15CA12CA1 | |
| SCHEMBL11044754 | 0.81 | CALM1 (0.53) | CHRM2CALM1IGF1RALOX15CA12 | |
| SCHEMBL5075584 | 0.81 | DRD2 (0.60) | SMN1; SMN2 | |
| SCHEMBL1272900 | 0.80 | CALM1 (0.56) | CALM1SMN1; SMN2POLBIGF1RALOX15 | |
| SCHEMBL6465780 | 0.79 | CHRM2 (0.62) | CHRM2CALM1SMN1; SMN2IGF1RALOX15 | |
| SCHEMBL10571532 | 0.79 | CALM1 (0.69) | CHRM2CALM1IGF1RALOX15CA12 | |
| SCHEMBL11007798 | 0.79 | CALM1 (0.69) | CHRM2CALM1IGF1RALOX15CA12 | |
| SCHEMBL17400406 | 0.79 | CALM1 (0.69) | CHRM2CALM1IGF1RALOX15CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6040289-A | ACTIVE DRUG TREATING OBESITY | DR. KARL THOMAE GMBH (DE) | 2000-03-21 | — | — | US | disclosed |
| US-5962530-A | NEUROPEPTIDE Y ANTAGONIST | DR. KARL THOMAE GMBH (DE) | 1999-10-05 | — | — | US | disclosed |