Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 7/20 | 0.36 |
| ▸ | MAOA | P21397 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8163031 | 0.82 | KDM4E (0.51) | ALDH1A1KDM4EHPGDCA12CA2 | |
| SCHEMBL18073236 | 0.81 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDCA12CA2 | |
| SCHEMBL26829548 | 0.76 | ATM (0.46) | ALDH1A1KDM4EHPGDCA12CA2 | |
| SCHEMBL8195756 | 0.74 | KDM4E (0.42) | ALDH1A1KDM4EHPGDCA12CA2 | |
| SCHEMBL3548365 | 0.74 | NPC1 (0.46) | ALDH1A1KDM4EHPGDATMSMN1; SMN2 | |
| SCHEMBL8187218 | 0.72 | MEN1 (0.41) | ALDH1A1KDM4EHPGDCA12CA2 | |
| SCHEMBL21468462 | 0.71 | KDM4E (0.54) | ALDH1A1KDM4EHPGDATMSMN1; SMN2 | |
| SCHEMBL2746509 | 0.71 | KDM4E (0.64) | ALDH1A1KDM4EHPGDL3MBTL1HSD17B10 | |
| SCHEMBL2884559 | 0.70 | CA12 (0.50) | ALDH1A1KDM4EHPGDCA12CA2 | |
| SCHEMBL24362256 | 0.70 | BAZ2B (0.41) | ALDH1A1KDM4EHPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078724-A2 | IMIDAZOLINDERIVATIVES THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |