SCHEMBL8196369

SCHEMBL8196369

COC(=O)N=C(N)OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11576363 1.00
SCHEMBL1820736 0.80
SCHEMBL9577028 0.80
SCHEMBL11250791 0.79 TSHR (0.37)
SCHEMBL11640902 0.79 ALOX15 (0.46)
SCHEMBL25791904 0.78
SCHEMBL5440140 0.78
SCHEMBL15866669 0.78
SCHEMBL11879706 0.76
SCHEMBL8195641 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6040289-A ACTIVE DRUG TREATING OBESITY DR. KARL THOMAE GMBH (DE) 2000-03-21 US disclosed
US-4816583-A 3- and 5-(bicyclic ether or bicyclic alkylene thioether) alkylene amino thiatriazines RORER PHARMACEUTICAL CORPORATION (US) 1989-03-28 US disclosed
US-4742055-A ANTISECRETORY, ANTIULCER RORER PHARMACEUTICAL CORPORATION (US) 1988-05-03 US disclosed
US-4727169-A ANTIULCER AGENTS RORER PHARMACEUTICAL CORPORATION (US) 1988-02-23 US disclosed
US-4704388-A ANTIULCER, CYTOPROTECTIVE RORER PHARMACEUTICAL CORPORATION (US) 1987-11-03 US disclosed
EP-0185684-A4 3- AND 5- ADBICYCLIC ETHER OR BICYCLIC ALKYLENE THIOETHER BDALKYLENE AMINO THIATRIAZINES, AND THEIR PHARMACEUTICAL USES. RORER INTERNAT OVERSEAS INC (US) 1986-09-22 EP disclosed
EP-0185684-A1 3- AND 5- ADBICYCLIC ETHER OR BICYCLIC ALKYLENE THIOETHER BDALKYLENE AMINO THIATRIAZINES, AND THEIR PHARMACEUTICAL USES RORER INTERNATIONAL (OVERSEAS) INC. (a Delaware corporation) (US) 1986-07-02 EP disclosed
US-4595683-A Gastrointestinal disorders, antiulcer agents WILLIAM H. RORER, INC. (US) 1986-06-17 US disclosed
WO-1985005105-A1 3- AND 5- ADBICYCLIC ETHER OR BICYCLIC ALKYLENE THIOETHER BDALKYLENE AMINO THIATRIAZINES, AND THEIR PHARMACEUTICAL USES RORER INTERNATIONAL (OVERSEAS) INC. (US) 1985-11-21 WO disclosed
US-4353913-A ANTHELMINTICS BAYER AKTIENGESELLSCHAFT (DE) 1982-10-12 US disclosed
US-4254143-A PARACITICIDES; LIVER FLUKES HOECHST AKTIENGESELLSCHAFT (DE) 1981-03-03 US disclosed
US-4121921-A ALLOPHANIMIDATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-10-24 US disclosed
US-4075201-A BIS CARBAMATE DERIVATIVES OF DIAZETIDINE DIONES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-02-21 US disclosed
US-4045473-A ALLOPHANIMIDATE INTERMEDIATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-08-30 US disclosed
US-4014924-A SELECTIVE HERBICIDES AND SOIL STERILANTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-03-29 US disclosed
US-3989501-A S-TRIAZINEDIONE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-11-02 US disclosed
US-3973947-A 1,3,5-Triazinediones and their use as selective herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-08-10 US disclosed
US-3959331-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-05-25 US disclosed
US-3951971-A SELECTIVE HERBICIDES FUCHS JULIUS JAKOB 1976-04-20 US disclosed
US-3933469-A ALLOPHANIMIDATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-01-20 US disclosed