Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8196976 | 0.89 | PDE10A (0.33) | PDE10A | |
| SCHEMBL8199014 | 0.89 | PDE10A (0.33) | PDE10A | |
| SCHEMBL8194003 | 0.89 | PDE10A (0.33) | PDE10A | |
| SCHEMBL8199009 | 0.89 | PDE10A (0.33) | PDE10A | |
| SCHEMBL2066415 | 0.88 | AR (0.38) | PDE10A | |
| SCHEMBL3514940 | 0.88 | AR (0.38) | PDE10A | |
| SCHEMBL2068713 | 0.88 | AR (0.38) | PDE10A | |
| SCHEMBL8199221 | 0.84 | SMPD3 (0.39) | PDE10A | |
| SCHEMBL8194229 | 0.82 | PIK3CA (0.31) | — | |
| SCHEMBL8185320 | 0.82 | PIK3CA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | claimed |
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | disclosed |