Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8194003 | 1.00 | PDE10A (0.33) | PDE10A | |
| SCHEMBL8199009 | 1.00 | PDE10A (0.33) | PDE10A | |
| SCHEMBL8196976 | 1.00 | PDE10A (0.33) | PDE10A | |
| SCHEMBL8196445 | 0.89 | PDE10A (0.32) | PDE10A | |
| SCHEMBL8194229 | 0.89 | PIK3CA (0.31) | — | |
| SCHEMBL8185318 | 0.89 | PIK3CA (0.31) | — | |
| SCHEMBL8185320 | 0.89 | PIK3CA (0.31) | — | |
| SCHEMBL8192241 | 0.86 | ADK (0.38) | — | |
| SCHEMBL8192237 | 0.86 | ADK (0.38) | — | |
| SCHEMBL17316302 | 0.81 | CHRM3 (0.34) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | claimed |
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | disclosed |