SCHEMBL819646

SCHEMBL819646

C/C(=C\c1cccc2ccccc12)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.68
AKR1C3 P42330 1/20 0.53
MTNR1A P48039 1/20 0.53
MTNR1B P49286 1/20 0.53
ALDH1A1 P00352 3/20 0.50
MAPT P10636 2/20 0.50
HPGD P15428 2/20 0.50
MEN1 O00255 1/20 0.50
GAA P10253 1/20 0.50
CRHBP P24387 1/20 0.50
HTT P42858 1/20 0.50
KMT2A Q03164 1/20 0.50
CRHR2 Q13324 1/20 0.50
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
SMPD2 O60906 1/20 0.44
NR4A2 P43354 2/20 0.44
NR4A1 P22736 1/20 0.44
NR4A3 Q92570 1/20 0.44
F2 P00734 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL36974 1.00 KDM4E (0.68) KDM4EAKR1C3MTNR1AMTNR1BALDH1A1
SCHEMBL17310558 0.90 KDM4E (0.57) KDM4EAKR1C3MTNR1AMTNR1BALDH1A1
SCHEMBL8746664 0.89 AKR1C3 (0.55) KDM4EAKR1C3MTNR1AMTNR1BALDH1A1
SCHEMBL11142704 0.89 AKR1C3 (0.55) KDM4EAKR1C3MTNR1AMTNR1BALDH1A1
SCHEMBL8746661 0.85 AKR1C3 (0.61) KDM4EAKR1C3ALDH1A1MAPTHPGD
SCHEMBL767171 0.85 KDM4E (0.51) KDM4EAKR1C3MTNR1AMTNR1BALDH1A1
SCHEMBL767170 0.85 KDM4E (0.51) KDM4EAKR1C3MTNR1AMTNR1BALDH1A1
SCHEMBL553715 0.84 KDM4E (0.57) KDM4EMTNR1AMTNR1BALDH1A1MAPT
SCHEMBL553714 0.84 KDM4E (0.57) KDM4EMTNR1AMTNR1BALDH1A1MAPT
SCHEMBL31602276 0.84 KDM4E (0.57) KDM4EMTNR1AMTNR1BALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117858592-A Efficient and stable perovskite thin film, solar cell device and preparation method 西安天交新能源有限公司 2024-04-09 CN claimed
EP-3368593-B1 IMPROVED BINDER COMPOSITIONS AND USES THEREOF KNAUF INSULATION SPRL (BE) 2023-12-06 EP claimed
EP-3839018-B1 HIGH VISCOSITY INDEX COMB POLYMER VISCOSITY MODIFIERS AND METHODS OF MODIFYING LUBRICANT VISCOSITY USING SAME INFINEUM INT LTD (GB) 2023-10-18 EP claimed
EP-3494186-B1 INKJET INK COMPOSITION HEWLETT PACKARD DEVELOPMENT CO (US) 2020-04-15 EP claimed
WO-2019034597-A1 FORCE-RESPONSIVE POLYMERSOMES AND NANOREACTORS; PROCESSES UTILIZING THE SAME ADOLPHE MERKLE INSTITUTE, UNIVERSITY OF FRIBOURG (CH) 2019-02-21 WO claimed
EP-1287047-B1 PHOTO-POLYMERS AND USE THEREOF TERAHERTZ PHOTONICS LTD (GB) 2008-08-13 EP claimed
US-20080031918-A1 BARRIERS FOR POLYMERIC COATINGS SURMODICS, INC. 2008-02-07 US claimed
JP-2007532197-A 2007-11-15 JP claimed
EP-1567203-B1 BARRIERS FOR BIOACTIVE AGENT-CONTAINING POLYMERIC COATINGS SURMODICS INC (US) 2007-09-26 EP claimed
JP-3954616-B2 2007-08-08 JP claimed
EP-0973636-B1 TRANSPARENT ARTICLE WITH RADIAL REFRACTIVE INDEX GRADIENT AND PROCESS FOR ITS MANUFACTURE ESSILOR INT (FR) 2003-01-02 EP claimed
US-20020188037-A1 Method and system for providing bioactive agent release coating Surmodics Coatings, LLC 2002-12-12 US claimed
EP-0661357-B1 Polymeric pigment dispersants for use in coating compositions BASF CORP (US) 2001-10-31 EP claimed
EP-0797785-B1 TEMPERATURE STABLE AND SUNLIGHT PROTECTED PHOTOCHROMIC ARTICLES CORNING INC (US) 2000-05-10 EP claimed
EP-0973636-A1 TRANSPARENT ARTICLE WITH RADIAL REFRACTIVE INDEX GRADIENT AND PROCESS FOR ITS MANUFACTURE ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2000-01-26 EP claimed
WO-1998045108-A1 TRANSPARENT ARTICLE WITH RADIAL REFRACTIVE INDEX GRADIENT AND PROCESS FOR ITS MANUFACTURE ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 1998-10-15 WO claimed
EP-0549610-B1 COPOLYMERIZATION PROCESS AND OPTICAL COPOLYMER PRODUCED THEREFROM AKZO NOBEL NV (NL) 1996-05-22 EP claimed
EP-0589340-B1 Urea-modified copolymers as dispersants for pigments in coating compositions BASF CORP (US) 1996-03-06 EP claimed
US-5349035-A Bisphenol diacrylate AKZO NOBEL N.V. (NL) 1994-09-20 US claimed
EP-0187870-B1 PATTERN FORMATION Nippon Telegraph and Telephone Corporation (JP) 1990-05-23 EP claimed