SCHEMBL819647

SCHEMBL819647

C=C(Cc1cccc2ccccc12)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.68
ATM Q13315 1/20 0.53
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
CYP1A2 P05177 1/20 0.50
KDM4E B2RXH2 1/20 0.50
LMNA P02545 1/20 0.50
HPGD P15428 1/20 0.50
PTGER4 P35408 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
CTNNB1 P35222 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.48
ACP3 P15309 1/20 0.47
BCHE P06276 1/20 0.47
MAPT P10636 1/20 0.46
POLB P06746 1/20 0.46
SIRT5 Q9NXA8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26180948 0.90 TDP1 (0.56) TDP1ATMMEN1KMT2ACYP1A2
SCHEMBL3423766 0.89 TDP1 (0.50) TDP1ATMMEN1KMT2ACYP1A2
SCHEMBL3422965 0.85 TDP1 (0.46) TDP1ATMMEN1KMT2ACYP1A2
SCHEMBL2243225 0.85 TDP1 (0.49) TDP1ATMMEN1KMT2ACYP1A2
SCHEMBL14351646 0.84 TDP1 (0.61) TDP1ATMMEN1KMT2ACYP1A2
SCHEMBL4084717 0.84 TDP1 (0.61) TDP1ATMMEN1KMT2ALMNA
SCHEMBL11558750 0.83 TDP1 (0.47) TDP1ATMMEN1KMT2ACYP1A2
SCHEMBL1989843 0.83 TDP1 (0.54) TDP1CYP1A2KDM4ECTNNB1ACP3
SCHEMBL8746636 0.82 AKR1B1 (0.46) TDP1MEN1KMT2ACYP1A2KDM4E
SCHEMBL3422141 0.82 TDP1 (0.46) TDP1ATMMEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118355112-A Hydrogel particles as feeder cells and as synthetic antigen presenting cells 弹弓生物科学公司 2024-07-16 CN claimed
CN-113264861-B Preparation method of alkyl dithiocarbamate 河南农业大学 2022-08-26 CN claimed
CN-113264861-A Preparation method of alkyl dithiocarbamate 河南农业大学 2021-08-17 CN claimed
EP-3735439-A1 STABLE ORGANIC LIGHT EMITTING COATING Yissum Research Development Company of the Hebrew University of Jerusalem Ltd (IL) 2020-11-11 EP claimed
WO-2019135223-A1 STABLE ORGANIC LIGHT EMITTING COATING YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2019-07-11 WO claimed
EP-1740235-B1 COATING COMPOSITIONS FOR BIOACTIVE AGENTS SURMODICS INC (US) 2009-07-22 EP claimed
US-7544673-B2 Coating compositions for bioactive agents SURMODICS, INC. (US) 2009-06-09 US claimed
US-7541048-B2 Coating compositions for bioactive agents SURMODICS, INC. (US) 2009-06-02 US claimed
US-20080031918-A1 BARRIERS FOR POLYMERIC COATINGS SURMODICS, INC. 2008-02-07 US claimed
JP-2007532197-A 2007-11-15 JP claimed
US-20040111144-A1 Barriers for polymeric coatings Surmodics Coatings, LLC 2004-06-10 US claimed
WO-2003105920-A1 METHOD AND SYSTEM FOR PROVIDING BIOACTIVE AGENT RELEASE COATING SURMODICS, INC. (US) 2003-12-24 WO claimed
WO-2003105919-A1 BIOACTIVE AGENT RELEASE COATING AND CONTROLLED HUMIDITY METHOD SURMODICS, INC. (US) 2003-12-24 WO claimed
WO-2003105918-A1 BIOACTIVE AGENT RELEASE COATING WITH AROMATIC POLY(METH)ACRYLATES SURMODICS, INC. (US) 2003-12-24 WO claimed
US-20030232087-A1 Bioactive agent release coating with aromatic poly(meth)acrylates Surmodics Coatings, LLC 2003-12-18 US claimed
US-20030232122-A1 Bioactive agent release coating and controlled humidity method Surmodics Coatings, LLC 2003-12-18 US claimed
US-20020188037-A1 Method and system for providing bioactive agent release coating Surmodics Coatings, LLC 2002-12-12 US claimed
US-20010026945-A1 Microparticle enhanced light scattering agglutination assay ROCHE DIAGNOSTICS OPERATIONS, INC. 2001-10-04 US claimed
EP-0549610-B1 COPOLYMERIZATION PROCESS AND OPTICAL COPOLYMER PRODUCED THEREFROM AKZO NOBEL NV (NL) 1996-05-22 EP claimed
US-5349035-A Bisphenol diacrylate AKZO NOBEL N.V. (NL) 1994-09-20 US claimed