Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL614756 | 0.78 | KDM4E (0.52) | LMNAKDM4EALDH1A1CYP2C19MAPT | |
| SCHEMBL2037934 | 0.78 | SMN1; SMN2 (0.40) | LMNAKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL13717521 | 0.76 | SMN1; SMN2 (0.40) | KDM4EALDH1A1POLB | |
| SCHEMBL12490138 | 0.73 | GPR119 (0.42) | LMNAALDH1A1POLB | |
| SCHEMBL20244719 | 0.73 | POLB (0.36) | LMNAKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL12490123 | 0.73 | GPR119 (0.43) | LMNAKDM4EALDH1A1CYP2C19POLB | |
| SCHEMBL18484646 | 0.73 | PANK3 (0.43) | LMNAKDM4EALDH1A1POLB | |
| SCHEMBL4775116 | 0.73 | LMNA (0.36) | LMNA | |
| SCHEMBL7086842 | 0.72 | KDM4E (0.61) | KDM4EALDH1A1CYP2C19HTR1APOLB | |
| SCHEMBL1231550 | 0.72 | POLB (0.50) | LMNAKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | claimed |
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | disclosed |