Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 13/20 | 0.61 |
| ▸ | CA1 | P00915 | 9/20 | 0.61 |
| ▸ | CA9 | Q16790 | 7/20 | 0.61 |
| ▸ | CA12 | O43570 | 6/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.61 |
| ▸ | CA4 | P22748 | 3/20 | 0.61 |
| ▸ | CA7 | P43166 | 3/20 | 0.61 |
| ▸ | CA6 | P23280 | 2/20 | 0.61 |
| ▸ | CA5A | P35218 | 2/20 | 0.61 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.61 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5436203 | 0.89 | CA2 (0.64) | CA2CA1CA9CA12CA14 | |
| SCHEMBL5277396 | 0.88 | CA2 (0.65) | CA2CA1CA9CA12CA14 | |
| SCHEMBL185757 | 0.85 | CA2 (0.61) | CA2CA1CA9CA12CA14 | |
| SCHEMBL31510169 | 0.83 | TSHR (0.50) | CA2CA1CA9CA12CA14 | |
| SCHEMBL30839505 | 0.83 | HTR6 (0.69) | CA2CA1CA9CA12CA14 | |
| SCHEMBL3735049 | 0.83 | HTR6 (0.69) | CA2CA1CA9CA12CA14 | |
| SCHEMBL28802276 | 0.83 | CA1 (0.59) | CA2CA1CA9CA12CA14 | |
| SCHEMBL23012488 | 0.81 | HTR6 (0.45) | CA2CA1CA9CA12CA14 | |
| SCHEMBL3997064 | 0.81 | GRM2 (0.48) | CA2CA1CA9CA12CA14 | |
| SCHEMBL13925829 | 0.81 | CA2 (0.61) | CA2CA1CA9CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166064-A | Sulfonyl urea derivatives and their use in the control of interleukin-1 activity | PFIZER INC (US) | 2000-12-26 | — | — | US | disclosed |