Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | ADK | P55263 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3821746 | 1.00 | LMNA (0.32) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL8184085 | 0.92 | ADORA2A (0.33) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL3826075 | 0.92 | ADORA2A (0.33) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL3827289 | 0.91 | LMNA (0.35) | LMNAALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL8184069 | 0.91 | LMNA (0.35) | LMNAALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL3825915 | 0.89 | CA9 (0.32) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL8184762 | 0.89 | CA9 (0.32) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL8192637 | 0.88 | CA9 (0.31) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL7206013 | 0.88 | CA9 (0.31) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL8196689 | 0.85 | CA9 (0.32) | LMNAALDH1A1TP53MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060183-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999040099-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-08-12 | — | — | WO | disclosed |