Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ADK | P55263 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8192637 | 1.00 | CA9 (0.31) | CA9CA12CA1CA2ALDH1A1 | |
| SCHEMBL3825915 | 0.91 | CA9 (0.32) | CA9CA12CA1CA2ALDH1A1 | |
| SCHEMBL8184762 | 0.91 | CA9 (0.32) | CA9CA12CA1CA2ALDH1A1 | |
| SCHEMBL3821746 | 0.88 | LMNA (0.32) | CA9CA12CA1CA2ALDH1A1 | |
| SCHEMBL8197142 | 0.88 | LMNA (0.32) | CA9CA12CA1CA2ALDH1A1 | |
| SCHEMBL8196689 | 0.87 | CA9 (0.32) | CA9CA12CA1CA2ALDH1A1 | |
| SCHEMBL3825432 | 0.87 | CA9 (0.32) | CA9CA12CA1CA2ALDH1A1 | |
| SCHEMBL3820964 | 0.87 | ADK (0.39) | CA9CA12CA1CA2ALDH1A1 | |
| SCHEMBL8184085 | 0.86 | ADORA2A (0.33) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL3826075 | 0.86 | ADORA2A (0.33) | ALDH1A1LMNATP53MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060183-B1 | 5'-DEOXYCYTIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |
| US-6005098-A | 5'deoxycytidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1999-12-21 | — | — | US | disclosed |