Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200416 | 0.81 | PIM1 (0.49) | MCL1KMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL8187979 | 0.79 | MCL1 (0.46) | MCL1KMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL9219618 | 0.79 | DHODH (0.45) | MCL1CSNK2A2CSNK2BCSNK2A1MAPT | |
| SCHEMBL8199806 | 0.76 | S1PR4 (0.41) | KMT2AMEN1MAPTHPGDRAB9A | |
| SCHEMBL8202256 | 0.76 | S1PR4 (0.39) | KMT2AMEN1NPSR1CSNK2A2CSNK2B | |
| SCHEMBL8201679 | 0.75 | S1PR4 (0.42) | KMT2AMEN1NPSR1MAPTRAB9A | |
| SCHEMBL27344482 | 0.75 | GPBAR1 (0.37) | ALDH1A1CSNK2A2CSNK2BCSNK2A1PIM1 | |
| SCHEMBL9220776 | 0.74 | KMT2A (0.46) | MCL1KMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL27318048 | 0.73 | S1PR4 (0.37) | KMT2AMEN1MAPT | |
| SCHEMBL8189218 | 0.72 | S1PR4 (0.47) | KMT2AMEN1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36832-E | AN ANTICHOLESTEROL AGENT TREATING HYPERCHOLESTEROLEMIA | NIHON NOHYAKU CO., LTD (JP) | 2000-08-22 | — | — | US | disclosed |
| CN-1051311-C | N-heteroaryl-n'-phenylurea derivatives, their production and use | NIHON NOHYAKU CO LTD (JP) | 2000-04-12 | — | — | CN | disclosed |
| EP-0613894-B1 | N-Heteroaryl-N'-phenylurea derivatives, their production and use | NIHON NOHYAKU CO LTD (JP) | 1999-05-06 | — | — | EP | disclosed |
| US-5464863-A | Anticholesterol agents | NIHON NOHYAKU CO., LTD. (JP) | 1995-11-07 | — | — | US | disclosed |
| CN-1100417-A | N-heteroaryl-n'-phenylurea derivatives, their production and use | NIHON NOHYAKU CO LTD (JP) | 1995-03-22 | — | — | CN | disclosed |
| EP-0613894-A1 | N-Heteroaryl-N'-phenylurea derivatives, their production and use | NIHON NOHYAKU CO., LTD. (JP) | 1994-09-07 | — | — | EP | disclosed |