Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27318048 | 0.82 | S1PR4 (0.37) | MAPTS1PR4GRM2MAPK14 | |
| SCHEMBL27408657 | 0.77 | S1PR4 (0.32) | MAPTS1PR4MAPK14 | |
| SCHEMBL8196653 | 0.77 | MAPT (0.44) | KDM4ETDP1ALDH1A1GAAMAPT | |
| SCHEMBL8197213 | 0.75 | MCL1 (0.43) | KDM4EALDH1A1MAPTHPGDCSNK2A2 | |
| SCHEMBL8199806 | 0.68 | S1PR4 (0.41) | MAPTHPGDTSHRSMN1; SMN2S1PR4 | |
| SCHEMBL8202256 | 0.67 | S1PR4 (0.39) | MAPTS1PR4CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL27456487 | 0.67 | SCN9A (0.40) | GPBAR1KDM4EADKALDH1A1GAA | |
| SCHEMBL8201679 | 0.66 | S1PR4 (0.42) | MAPTS1PR4 | |
| SCHEMBL27315659 | 0.66 | THRB (0.38) | KDM4ETDP1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8201682 | 0.64 | RAB9A (0.43) | KDM4ETDP1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051311-C | N-heteroaryl-n'-phenylurea derivatives, their production and use | NIHON NOHYAKU CO LTD (JP) | 2000-04-12 | — | — | CN | disclosed |
| CN-1100417-A | N-heteroaryl-n'-phenylurea derivatives, their production and use | NIHON NOHYAKU CO LTD (JP) | 1995-03-22 | — | — | CN | disclosed |