Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Benzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL15439482 | 0.94 | FFAR3 (0.47) | FFAR3LCKFYNSMN1; SMN2 | |
| Acetic Acid SCHEMBL4544141 | 0.91 | FFAR3 (0.44) | FFAR3LCKFYN | |
| Acetic Acid SCHEMBL6125476 | 0.91 | FFAR3 (0.44) | FFAR3LCKFYN | |
| Acetic Acid SCHEMBL4539715 | 0.91 | FFAR3 (0.44) | FFAR3LCKFYN | |
| Acetic Acid SCHEMBL4543690 | 0.91 | FFAR3 (0.44) | FFAR3LCKFYN | |
| Acetic Acid SCHEMBL28871134 | 0.88 | FFAR3 (0.41) | FFAR3LCKFYN | |
| Acetic Acid SCHEMBL1704983 | 0.88 | — | — | |
| Acetone SCHEMBL4379179 | 0.84 | LMNA (0.43) | FFAR3LCKFYNSMN1; SMN2 | |
| Toluene SCHEMBL1308696 | 0.84 | LMNA (0.46) | GAASMN1; SMN2 | |
| Acetic Acid SCHEMBL8158174 | 0.84 | FFAR3 (0.58) | FFAR3LCKFYNSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240216444-A1 | DESIGNED BACTERIAL COMPOSITIONS | SERES THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | US | disclosed |
| US-20240180156-A1 | BIOACTIVE COMPOSITION FOR IMPROVING STRESS TOLERANCE OF PLANTS | FYTEKO (BE) | 2024-06-06 | — | — | US | disclosed |
| US-11896009-B2 | Bioactive composition for improving stress tolerance of plants | FYTEKO (BE) | 2024-02-13 | — | — | US | disclosed |
| EP-3349578-B1 | BIOACTIVE COMPOSITION FOR IMPROVING STRESS TOLERANCE OF PLANTS | FYTEKO (BE) | 2023-06-07 | — | — | EP | disclosed |
| US-20190247447-A1 | DESIGNED BACTERIAL COMPOSITIONS | SERES THERAPEUTICS, INC. | 2019-08-15 | — | — | US | disclosed |
| EP-3380108-A2 | DESIGNED BACTERIAL COMPOSITIONS | Seres Therapeutics, Inc. (US) | 2018-10-03 | — | — | EP | disclosed |
| US-20180242579-A1 | BIOACTIVE COMPOSITION FOR IMPROVING STRESS TOLERANCE OF PLANTS | FYTEKO (BE) | 2018-08-30 | — | — | US | disclosed |
| WO-2017091783-A2 | DESIGNED BACTERIAL COMPOSITIONS | SERES THERAPEUTICS, INC. (US) | 2017-06-01 | — | — | WO | disclosed |
| EP-0711148-B1 | BIPHASIC MULTILAMELLAR LIPID VESICLES | PHARMADERM LAB LTD (CA) | 2000-08-30 | — | — | EP | disclosed |
| US-5993851-A | MIXING AN OIL-IN-WATER EMULSION WITH VESICLE-FORMING LIPIDS TO FORM LIPOSOMES HAVING A LIPID-BILAYER MEMBRANE COMPOSED OF THE VESICLE-FORMING LIPIDS AND CONTAINING THE OIL-IN-WATER EMULSION IN THE CENTRAL CORE COMPARTMENT. | PHARMADERM LABORATORIES, LTD. (CA) | 1999-11-30 | — | — | US | disclosed |
| EP-0101294-A2 | Composition for protecting and healing gastro-duodenal mucosa and the liver of mammals | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1984-02-22 | — | — | EP | disclosed |
| US-4399147-A | Prostaglandin 12 analogues and their pharmaceutical compositions | ONO PHARMACEUTICAL CO. LTD. (JP) | 1983-08-16 | — | — | US | disclosed |
| US-4390548-A | Trans-Δ2 -pge alkylsulphonyl amides | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-06-28 | — | — | US | disclosed |
| US-4321275-A | ANIMAL HUSBANDRY | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-03-23 | — | — | US | disclosed |
| US-4304715-A | Enkephalin analogues | HUDSON DEREK | 1981-12-08 | — | — | US | disclosed |
| US-RE30731-E | Enkephalin analogues | Hudson, Derek (GB) | 1981-09-01 | — | — | US | disclosed |
| US-4198398-A | Enkephalin analogues | HUDSON DEREK (GB) | 1980-04-15 | — | — | US | disclosed |
| US-4097579-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, MUSCLE RELAXANTS | SYNTEX (U.S.A.) INC. (US) | 1978-06-27 | — | — | US | disclosed |
| US-4089969-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, SMOOTH MUSCLE RELAXANT | SYNTEX (U.S.A.) INC. (US) | 1978-05-16 | — | — | US | disclosed |
| US-4087539-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, SMOOTH MUSCLE RELAXANTS | SYNTEX (U.S.A.) INC. (US) | 1978-05-02 | — | — | US | disclosed |