Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TLR4 | O00206 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL817737 | 0.78 | ALDH1A1 (0.38) | TLR4ALDH1A1TSHRHSD17B10KDM4E | |
| SCHEMBL818501 | 0.76 | ALDH1A1 (0.36) | ALDH1A1TSHRKDM4EHPGDATM | |
| SCHEMBL13671086 | 0.76 | KCNH2 (0.40) | KCNH2TLR4ALDH1A1TSHRHSD17B10 | |
| SCHEMBL818284 | 0.75 | ALDH1A1 (0.38) | ALDH1A1TSHRHSD17B10GAA | |
| SCHEMBL820015 | 0.74 | L3MBTL1 (0.40) | ALDH1A1TSHRKDM4EHPGDATM | |
| SCHEMBL818754 | 0.73 | TSHR (0.38) | KCNH2ALDH1A1TSHRHSD17B10KDM4E | |
| SCHEMBL818714 | 0.73 | ALDH1A1 (0.43) | ALDH1A1TSHRHSD17B10KDM4ECYP3A4 | |
| SCHEMBL1101682 | 0.70 | KCNH2 (0.37) | KCNH2TLR4ALDH1A1TSHRHSD17B10 | |
| SCHEMBL20383516 | 0.70 | KCNH2 (0.37) | KCNH2TLR4ALDH1A1TSHRHSD17B10 | |
| SCHEMBL20383515 | 0.69 | KCNH2 (0.36) | KCNH2TLR4ALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |