Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 6/20 | 0.44 |
| ▸ | FNTB | P49356 | 6/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8193373 | 0.89 | ITGB3 (0.33) | FNTAFNTBPGGT1B | |
| SCHEMBL8193354 | 0.87 | FNTA (0.39) | FNTAFNTB | |
| SCHEMBL7563333 | 0.84 | FNTA (0.50) | FNTAFNTB | |
| SCHEMBL8185614 | 0.83 | BRS3 (0.43) | TDP1 | |
| SCHEMBL8194554 | 0.81 | CTSA (0.34) | — | |
| SCHEMBL7562986 | 0.80 | FNTA (0.43) | FNTAFNTBPGGT1BTDP1 | |
| SCHEMBL7569644 | 0.80 | FNTA (0.54) | FNTAFNTBPGGT1BTDP1 | |
| SCHEMBL8199840 | 0.79 | FNTA (0.39) | FNTAFNTBPGGT1B | |
| SCHEMBL8197818 | 0.79 | FNTA (0.48) | FNTAFNTB | |
| SCHEMBL7563110 | 0.78 | FNTA (0.57) | FNTAFNTBPGGT1BTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025088-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | AstraZeneca UK Limited (GB) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999020611-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | ZENECA LIMITED (GB) | 1999-04-29 | — | — | WO | disclosed |