SCHEMBL8198250

SCHEMBL8198250

O=C(Oc1cccc(I)c1)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.61
MAPT P10636 3/20 0.61
TDP1 Q9NUW8 3/20 0.61
MEN1 O00255 1/20 0.61
ALDH1A1 P00352 2/20 0.54
PARP10 Q53GL7 1/20 0.51
NSD2 O96028 1/20 0.51
CA12 O43570 1/20 0.49
POLB P06746 1/20 0.49
CA9 Q16790 1/20 0.49
ESR1 P03372 2/20 0.49
ESR2 Q92731 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
PKM P14618 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1785471 0.88 KMT2A (0.69) KMT2AMAPTTDP1MEN1ALDH1A1
SCHEMBL23064097 0.83 KMT2A (0.62) KMT2AMAPTTDP1MEN1ALDH1A1
SCHEMBL8897103 0.83 AKR1C3 (0.67) KMT2AMAPTTDP1MEN1ALDH1A1
SCHEMBL1870544 0.82 PARP10 (0.70) KMT2AMAPTTDP1MEN1ALDH1A1
SCHEMBL31888 0.82 PARP10 (0.70) KMT2AMAPTTDP1MEN1ALDH1A1
SCHEMBL7175937 0.81 ALOX5 (0.66) KMT2AMAPTTDP1MEN1ALDH1A1
Benzoic Acid 3-Hydroxyphenyl Ester SCHEMBL78117 0.81 ESR1 (0.71) KMT2AMAPTTDP1MEN1ALDH1A1
Benzoic Acid 3-Hydroxyphenyl Ester SCHEMBL31650796 0.81 ESR1 (0.71) KMT2AMAPTTDP1MEN1ALDH1A1
SCHEMBL9356640 0.81 AKR1C3 (0.65) KMT2AMAPTTDP1MEN1ALDH1A1
SCHEMBL28557620 0.81 KMT2A (0.61) KMT2AMAPTTDP1MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6117562-A A THERMAL IMAGE TRANSFER INK LAYER FORMED ON THE SUPPORT; INK LAYER COMPRISING A COLORING AGENT, A RESIN AND A PLASTICIZER FOR LOWERING THE MELT VISCOSITY OF RESIN RICOH COMPANY, LTD. (JP) 2000-09-12 US disclosed
US-5716477-A CONSISTS OF A SUPPORT AND THERMAL IMAGE TRANSFER INK LAYER FORMED ON SAID SUPPORT CONSISTS OF A COLORING AGENT AND A PLASTICIZER FOR LOWERING MELT VISCOSITY OF THE RESIN, HIGH THERMOSENSITIVITY ON CLOTH, PLASTIC, OR PAPER RECEIVER RICOH COMPANY, LTD. (JP) 1998-02-10 US disclosed
US-4562448-A Heat-sensitive transfer medium RICOH CO., LTD. (JP) 1985-12-31 US disclosed