SCHEMBL819845

SCHEMBL819845

C=CCC(CC=C)(C(=O)OC(C)C)C(=O)OC(C)C

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
PTPN1 P18031 1/20 0.36
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
LMNA P02545 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29220263 0.87 LMNA (0.33) TSHRPTPN1LMNA
SCHEMBL29220165 0.82 TSHR (0.34) TSHRMEN1KMT2AHCAR2TDP1
SCHEMBL29220405 0.80 PTPN1 (0.34) TSHRPTPN1MEN1KMT2AHCAR2
SCHEMBL29220137 0.80 MEN1 (0.39) TSHRMEN1KMT2AHCAR2TDP1
SCHEMBL29220419 0.80 MAPT (0.35) TSHRMEN1KMT2AHCAR2TDP1
SCHEMBL3960417 0.76 TSHR (0.52) TSHRTDP1LMNA
SCHEMBL770755 0.76 CYP2C19 (0.39) TSHRHCAR2TDP1LMNA
SCHEMBL5806972 0.74 ALDH1A1 (0.32) TSHRLMNA
SCHEMBL28977828 0.74 CYP3A4 (0.39) TSHRMEN1KMT2ATDP1
SCHEMBL6048653 0.73 TSHR (0.42) TSHRPTPN1MEN1KMT2AHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8247510-B2 Copolymer and production process thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-21 US disclosed
US-20110288250-A1 Copolymer and Production Process Thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-24 US disclosed
US-8044159-B2 Homopolymer and copolymer, and production process thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-10-25 US disclosed
CN-101248103-B Homopolymer and copolymer, and production process thereof SUMITOMO CHEMICAL CO 2011-04-13 CN disclosed
US-20090171054-A1 HOMOPOLYMER AND COPOLYMER, AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-02 US disclosed
WO-2009038031-A1 BLOCK COPOLYMER AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-26 WO disclosed
WO-2009038006-A1 RANDOM COPOLYMER AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-26 WO disclosed
US-20080214756-A1 CYCLIC OLEFIN-DIENE COPOLYMER AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-04 US disclosed
CN-101255220-A Cyclic olefin-diene copolymer and process for producing the same SUMITOMO CHEMICAL CO (JP) 2008-09-03 CN disclosed
CN-101248103-A Homopolymer and copolymer, and production process thereof SUMITOMO CHEMICAL CO (JP) 2008-08-20 CN disclosed
WO-2007023618-A1 HOMOPOLYMER AND COPOLYMER, AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-01 WO disclosed