Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 4/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8203684 | 0.89 | MC4R (0.46) | MC4RKCNH2LMNASMN1; SMN2HTT | |
| SCHEMBL6824821 | 0.87 | MC4R (0.43) | MC4RKCNH2LMNASMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL8201038 | 0.80 | LMNA (0.50) | KCNH2LMNANISCH | |
| Hydrochloric Acid SCHEMBL8203262 | 0.80 | NISCH (0.54) | NISCH | |
| Hydrochloric Acid SCHEMBL8197454 | 0.77 | ADRA1D (0.45) | NISCH | |
| Hydrochloric Acid SCHEMBL8197437 | 0.77 | NISCH (0.53) | MC4RPDCD1LG2CD274NISCH | |
| SCHEMBL6825218 | 0.77 | KCNH2 (0.43) | MC4RKCNH2PDCD1LG2CD274NISCH | |
| SCHEMBL8218532 | 0.77 | NISCH (0.38) | MC4RPDCD1LG2CD274NISCH | |
| Hydrochloric Acid SCHEMBL7738758 | 0.76 | KCNH2 (0.43) | MC4RKCNH2PDCD1LG2CD274NISCH | |
| Hydrochloric Acid SCHEMBL8194260 | 0.76 | NISCH (0.48) | NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078726-A1 | IMIDAZOLINE DERIVATIVES FOR THE TREATMENT OF DIABETES, ESPECIALLY TYPE II DIABETES | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |