Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.66 |
| ▸ | EBP | Q15125 | 1/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8728742 | 0.95 | SIGMAR1 (0.74) | SIGMAR1EBPTMEM97 | |
| SCHEMBL9075945 | 0.92 | SIGMAR1 (0.66) | SIGMAR1EBPTMEM97 | |
| SCHEMBL8201210 | 0.91 | SIGMAR1 (0.67) | SIGMAR1EBPTMEM97 | |
| SCHEMBL9077642 | 0.89 | SIGMAR1 (0.58) | SIGMAR1 | |
| SCHEMBL9077118 | 0.88 | SIGMAR1 (0.62) | SIGMAR1EBPTMEM97 | |
| SCHEMBL8196559 | 0.87 | SIGMAR1 (0.61) | SIGMAR1EBPTMEM97 | |
| SCHEMBL9077457 | 0.86 | SIGMAR1 (0.60) | SIGMAR1EBPTMEM97 | |
| SCHEMBL8731786 | 0.86 | SIGMAR1 (0.66) | SIGMAR1EBPTMEM97 | |
| SCHEMBL8196408 | 0.85 | SIGMAR1 (0.59) | SIGMAR1EBPTMEM97 | |
| SCHEMBL8198510 | 0.82 | PTGES (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717990-B1 | COMPOSITION FOR REMEDYING DRUG DEPENDENCE | TAISHO PHARMACEUTICAL CO LTD (JP) | 2000-05-24 | — | — | EP | disclosed |
| US-5495046-A | PSYCHOLOGICAL DISORDERS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1996-02-27 | — | — | US | disclosed |
| EP-0641766-A1 | ALKOXYPHENYLALKYLAMINE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-03-08 | — | — | EP | disclosed |