SCHEMBL8198655

SCHEMBL8198655

CSCC[C@H](NC(=O)c1ccc(C=C(Cc2ncc[nH]2)c2ccc(F)cc2)cc1-c1ccc(F)cc1)C(N)=O

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 10/20 0.41
FNTB P49356 10/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8207254 0.94 FNTA (0.47) FNTAFNTB
SCHEMBL8199776 0.92 FNTA (0.49) FNTAFNTB
SCHEMBL8213729 0.89 FNTA (0.37) FNTAFNTB
SCHEMBL8209424 0.89 FNTA (0.43) FNTAFNTB
SCHEMBL8199385 0.88 FNTA (0.52) FNTAFNTB
SCHEMBL8209147 0.86 FNTA (0.40) FNTAFNTB
SCHEMBL8209899 0.86 FNTA (0.40) FNTAFNTB
SCHEMBL8199451 0.85 FNTA (0.43) FNTAFNTB
SCHEMBL8207389 0.84 FNTA (0.40) FNTAFNTB
SCHEMBL8206519 0.84 NAMPT (0.38) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975603-A1 INHIBITORS OF FARNESYL PROTEIN TRANSFERASE ZENECA LIMITED (GB) 2000-02-02 EP claimed
WO-1998032741-A1 INHIBITORS OF FARNESYL PROTEIN TRANSFERASE ZENECA LIMITED (GB) 1998-07-30 WO claimed