Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 10/20 | 0.40 |
| ▸ | FNTB | P49356 | 10/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8198280 | 0.94 | FNTA (0.46) | FNTAFNTBPGGT1BCA1CA2 | |
| SCHEMBL8206389 | 0.94 | FNTA (0.46) | FNTAFNTBPGGT1BCA1CA2 | |
| SCHEMBL8250464 | 0.88 | NAMPT (0.34) | FNTAFNTBCA12CA9PGGT1B | |
| SCHEMBL8211056 | 0.86 | FNTA (0.40) | FNTAFNTBPGGT1BNAMPT | |
| SCHEMBL8198655 | 0.86 | FNTA (0.41) | FNTAFNTB | |
| SCHEMBL8209175 | 0.85 | CA2 (0.41) | CA1CA2NAMPT | |
| SCHEMBL8205624 | 0.84 | CA2 (0.46) | FNTAFNTBCA12CA9PGGT1B | |
| SCHEMBL8205467 | 0.82 | NAMPT (0.40) | NAMPT | |
| SCHEMBL8205943 | 0.82 | ERAP2 (0.40) | CA12CA9CA1CA2NAMPT | |
| SCHEMBL8205809 | 0.82 | FNTA (0.46) | FNTAFNTBPGGT1BCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975603-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 2000-02-02 | — | — | EP | claimed |
| WO-1998032741-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 1998-07-30 | — | — | WO | claimed |
| EP-0975603-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998032741-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 1998-07-30 | — | — | WO | disclosed |