Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206533 | 1.00 | LMNA (0.40) | LMNATDP1ALDH1A1TP53MAPT | |
| SCHEMBL3817265 | 0.87 | LMNA (0.46) | LMNATDP1ALDH1A1TP53MAPT | |
| SCHEMBL7210851 | 0.86 | LMNA (0.45) | LMNATDP1ALDH1A1TP53MAPT | |
| SCHEMBL8198893 | 0.86 | LMNA (0.45) | LMNATDP1ALDH1A1TP53MAPT | |
| SCHEMBL7204645 | 0.86 | LMNA (0.54) | LMNA | |
| SCHEMBL8194179 | 0.86 | LMNA (0.54) | LMNA | |
| SCHEMBL3817191 | 0.85 | LMNA (0.51) | LMNATDP1ALDH1A1TP53MAPT | |
| SCHEMBL8192660 | 0.83 | LMNA (0.42) | LMNATDP1ALDH1A1TP53MAPT | |
| SCHEMBL3821749 | 0.83 | LMNA (0.56) | LMNAALDH1A1MAPTTHRBSMN1; SMN2 | |
| SCHEMBL7209690 | 0.83 | LMNA (0.42) | LMNATDP1ALDH1A1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060183-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999040099-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-08-12 | — | — | WO | disclosed |