Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | DTYMK | P23919 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6902179 | 0.83 | TSHR (0.42) | TSHRALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL9192755 | 0.79 | TSHR (0.58) | TSHRALDH1A1MAPK1TDP1CYP3A4 | |
| SCHEMBL67864 | 0.79 | MAPK1 (0.60) | TSHRALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL11404158 | 0.79 | ALDH1A1 (0.41) | TSHRALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL10757303 | 0.78 | ATM (0.58) | TSHRALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL68365 | 0.78 | TSHR (0.60) | TSHRALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL9446983 | 0.78 | TSHR (0.56) | TSHRALDH1A1MAPK1HPGDSNCA | |
| SCHEMBL8461057 | 0.78 | TSHR (0.59) | TSHRALDH1A1MAPK1TDP1CYP3A4 | |
| SCHEMBL5178027 | 0.76 | TSHR (0.56) | TSHRALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL3295597 | 0.75 | TSHR (0.64) | TSHRALDH1A1MAPK1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000001674-A1 | PROCESS FOR MAKING 1,5-DISUBSTITUTED IMIDAZOLES | MERCK & CO., INC. (US) | 2000-01-13 | — | — | WO | disclosed |