Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27918973 | 0.89 | TSHR (0.52) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL13331284 | 0.84 | ALDH1A1 (0.66) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL216984 | 0.82 | TSHR (0.50) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL819488 | 0.82 | TSHR (0.46) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL28736719 | 0.81 | ALDH1A1 (0.45) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL16743631 | 0.81 | TSHR (0.52) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL15036528 | 0.81 | TSHR (0.52) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL27051341 | 0.81 | TSHR (0.48) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL6535136 | 0.80 | TSHR (0.61) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL27458673 | 0.80 | TSHR (0.61) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8513334-B2 | Functionalized polyurethane polyurea dispersions | BAYER MATERIALSCIENCE AG (DE) | 2013-08-20 | — | — | US | disclosed |
| EP-2398835-B1 | FUNCTIONALIZED POLYURETHANE POLYUREA DISPERSIONS | BAYER MATERIALSCIENCE AG (DE) | 2012-12-19 | — | — | EP | disclosed |
| EP-2398835-A1 | FUNCTIONALIZED POLYURETHANE POLYUREA DISPERSIONS | Bayer MaterialScience AG (DE) | 2011-12-28 | — | — | EP | disclosed |
| US-20110288204-A1 | FUNCTIONALIZED POLYURETHANE POLYUREA DISPERSIONS | BAYER MATERIAL SCIENCE AG (DE) | 2011-11-24 | — | — | US | disclosed |
| WO-2010094417-A1 | FUNCTIONALIZED POLYURETHANE POLYUREA DISPERSIONS | BAYER MATERIALSCIENCE AG (DE) | 2010-08-26 | — | — | WO | disclosed |
| EP-2221330-A1 | Functionalised polyurethane polyuric dispersions | Bayer MaterialScience AG (DE) | 2010-08-25 | — | — | EP | disclosed |