Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 7/20 | 0.43 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.42 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.42 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.42 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199243 | 0.90 | GRIN2B (0.46) | GRIN2BTAAR1GRIN1 | |
| SCHEMBL8199090 | 0.89 | GRIN2B (0.43) | GRIN2BPLAAT3PLAAT5PLAAT2PLAAT4 | |
| Hydrochloric Acid SCHEMBL8209834 | 0.88 | GRIN2B (0.46) | GRIN2BTAAR1GRIN1 | |
| SCHEMBL8211310 | 0.84 | OPRM1 (0.39) | GRIN2BCHRM2CHRM3GRIN1 | |
| SCHEMBL8199188 | 0.84 | GRIN2B (0.40) | GRIN2BCHRM2CHRM3TAAR1GRIN1 | |
| SCHEMBL8206272 | 0.83 | TAAR1 (0.46) | GRIN2BTAAR1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8205244 | 0.83 | TAAR1 (0.49) | GRIN2BTAAR1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8206280 | 0.83 | TAAR1 (0.46) | GRIN2BTAAR1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8209750 | 0.83 | TAAR1 (0.46) | GRIN2BTAAR1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8199053 | 0.83 | TAAR1 (0.50) | GRIN2BCHRM2CHRM3TAAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | claimed |
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | disclosed |