Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 6/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.38 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.38 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199243 | 0.92 | GRIN2B (0.46) | GRIN2BSIGMAR1GRIN1 | |
| SCHEMBL8199188 | 0.91 | GRIN2B (0.40) | GRIN2BMCHR1SIGMAR1GRIN1CHRM2 | |
| SCHEMBL8209728 | 0.90 | HRH1 (0.42) | GRIN2BMCHR1SIGMAR1GRIN1CHRM2 | |
| SCHEMBL8199533 | 0.89 | GRIN2B (0.43) | GRIN2BGRIN1CHRM2CHRM3ALDH1A1 | |
| SCHEMBL8205354 | 0.89 | MEN1 (0.43) | GRIN2BMCHR1SIGMAR1GRIN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8209834 | 0.88 | GRIN2B (0.46) | GRIN2BSIGMAR1GRIN1 | |
| SCHEMBL8205279 | 0.88 | GRIN2B (0.48) | GRIN2BMCHR1GRIN1CHRM2CHRM3 | |
| SCHEMBL8206072 | 0.86 | GRIN2B (0.48) | GRIN2BSIGMAR1ALDH1A1 | |
| SCHEMBL8211721 | 0.86 | MCHR1 (0.44) | GRIN2BMCHR1SIGMAR1GRIN1ALDH1A1 | |
| SCHEMBL8206272 | 0.86 | TAAR1 (0.46) | GRIN2BSIGMAR1GRIN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | disclosed |