Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL820227 | 0.91 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL819780 | 0.91 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL3684427 | 0.86 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2TDP1TSHR | |
| SCHEMBL820335 | 0.83 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL13331284 | 0.79 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL8458495 | 0.77 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2TDP1TSHR | |
| SCHEMBL28401907 | 0.76 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL819929 | 0.75 | TSHR (0.59) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL819488 | 0.74 | TSHR (0.46) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL216984 | 0.72 | TSHR (0.50) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8513334-B2 | Functionalized polyurethane polyurea dispersions | BAYER MATERIALSCIENCE AG (DE) | 2013-08-20 | — | — | US | disclosed |
| EP-2398835-B1 | FUNCTIONALIZED POLYURETHANE POLYUREA DISPERSIONS | BAYER MATERIALSCIENCE AG (DE) | 2012-12-19 | — | — | EP | disclosed |
| EP-2398835-A1 | FUNCTIONALIZED POLYURETHANE POLYUREA DISPERSIONS | Bayer MaterialScience AG (DE) | 2011-12-28 | — | — | EP | disclosed |
| US-20110288204-A1 | FUNCTIONALIZED POLYURETHANE POLYUREA DISPERSIONS | BAYER MATERIAL SCIENCE AG (DE) | 2011-11-24 | — | — | US | disclosed |
| WO-2010094417-A1 | FUNCTIONALIZED POLYURETHANE POLYUREA DISPERSIONS | BAYER MATERIALSCIENCE AG (DE) | 2010-08-26 | — | — | WO | disclosed |
| EP-2221330-A1 | Functionalised polyurethane polyuric dispersions | Bayer MaterialScience AG (DE) | 2010-08-25 | — | — | EP | disclosed |