Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730048 | 0.93 | ESR1 (0.45) | ESR1ESR2KMT2AMAPTKDM4E | |
| SCHEMBL20637289 | 0.84 | ESR1 (0.43) | ESR1ESR2KMT2AMAPTKDM4E | |
| SCHEMBL19273459 | 0.78 | SIGMAR1 (0.41) | ESR1ESR2KDM4ETSHRALDH1A1 | |
| SCHEMBL3982887 | 0.77 | AR (0.43) | TP53TSHRCYP3A4ALDH1A1NAAA | |
| SCHEMBL2101644 | 0.76 | NR1H2 (0.32) | ESR1ESR2KMT2AMAPTKDM4E | |
| SCHEMBL9849736 | 0.76 | KCNH2 (0.45) | KMT2ATP53TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL2272184 | 0.76 | KMT2A (0.32) | ESR1ESR2KMT2AMAPTKDM4E | |
| SCHEMBL10361208 | 0.76 | KCNH2 (0.45) | KMT2ATP53TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL28646795 | 0.76 | KCNH2 (0.45) | KMT2ATP53TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL20499846 | 0.74 | ESR1 (0.33) | ESR1ESR2KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6120962-A | TONERS FOR DEVELOPMENT OF LATENT IMAGES | RICOH COMPANY, LTD. (JP) | 2000-09-19 | — | — | US | disclosed |