Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.43 |
| ▸ | PPARG | P37231 | 8/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 3/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CCKAR | P32238 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8195869 | 0.80 | PPARA (0.41) | PPARAPPARGACEPPARDCTSK | |
| SCHEMBL805980 | 0.80 | NOS1 (0.40) | — | |
| SCHEMBL29832351 | 0.79 | PCSK9 (0.36) | — | |
| SCHEMBL606575 | 0.74 | PPARA (0.44) | PPARAPPARGACEPPARDCTSS | |
| SCHEMBL6739624 | 0.74 | PPARA (0.44) | PPARAPPARGACEPPARDCTSS | |
| SCHEMBL10246509 | 0.74 | PPARA (0.44) | PPARAPPARGACEPPARDCTSS | |
| SCHEMBL23259297 | 0.73 | TDP1 (0.40) | IDO1 | |
| SCHEMBL1033716 | 0.72 | PPARA (0.42) | PPARAPPARGACEPPARDCTSS | |
| SCHEMBL28853919 | 0.72 | PPARA (0.42) | PPARAPPARGACEPPARDCTSS | |
| SCHEMBL22755596 | 0.71 | TDP1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078723-A1 | PROCESS FOR THE PREPARATION OF BUTOXYCARBONYLIMINO COMPOUNDS AND INTERMEDIATES THEREFOR | GLAXO GROUP LIMITED (GB) | 2000-12-28 | — | — | WO | disclosed |