SCHEMBL805980

SCHEMBL805980

CC(C)(C)OC(=O)NC(=N)n1cccn1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 1/20 0.40
ELANE P08246 3/20 0.35
CYP17A1 P05093 3/20 0.35
PCSK9 Q8NBP7 1/20 0.34
NAMPT P43490 1/20 0.33
RAB9A P51151 2/20 0.32
ATR Q13535 1/20 0.32
FBP1 P09467 1/20 0.32
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PDE4B Q07343 1/20 0.31
F2 P00734 1/20 0.31
PLAU P00749 1/20 0.31
KLKB1 P03952 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29832351 0.85 PCSK9 (0.36) NOS1CYP17A1PCSK9NAMPTMEN1
SCHEMBL28208378 0.84 ELANE (0.36) NOS1ELANECYP17A1PCSK9NAMPT
SCHEMBL20591975 0.84 NOS1 (0.44) NOS1ELANEFBP1PDE4BF2
SCHEMBL23259297 0.83 TDP1 (0.40) NOS1PCSK9MEN1GAAKMT2A
SCHEMBL17666147 0.82 FBP1 (0.35) NOS1ELANECYP17A1PCSK9NAMPT
SCHEMBL126581 0.82 ELANE (0.35) NOS1ELANECYP17A1PCSK9NAMPT
SCHEMBL22755543 0.81 TDP1 (0.48) MEN1GAAKMT2A
SCHEMBL22755596 0.81 TDP1 (0.44) PCSK9MEN1GAAKMT2A
SCHEMBL22755562 0.80 KDM1A (0.43) NAMPTKMT2AL3MBTL1
SCHEMBL8199609 0.80 PPARA (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036560-A Radioactive medical isotope18F-labeled norepinephrine analogue as well as preparation method and application thereof 中国医学科学院阜外医院 2026-05-15 CN claimed
CN-122036560-A Radioactive medical isotope18F-labeled norepinephrine analogue as well as preparation method and application thereof 中国医学科学院阜外医院 2026-05-15 CN disclosed
EP-4655289-A1 SINGLE-MOLECULE PEPTIDE SEQUENCING USING GUANIDINYLATING AGENTS Glyphic Biotechnologies, Inc. (US) 2025-12-03 EP disclosed
US-12415828-B2 Modified oligonucleotides and methods for their synthesis NOOGEN LLC (RU) 2025-09-16 US disclosed
CN-119522092-A Multivalent molecule-based lipid nanoparticles for nucleic acid delivery 比奥-特里普公司 2025-02-25 CN disclosed
WO-2024159162-A1 SINGLE-MOLECULE PEPTIDE SEQUENCING USING GUANIDINYLATING AGENTS GLYPHIC BIOTECHNOLOGIES, INC. (US) 2024-08-02 WO disclosed
US-20240142876-A1 SEMICONDUCTOR SUBSTRATE MANUFACTURING METHOD AND COMPOSITION JSR CORPORATION (JP) 2024-05-02 US disclosed
US-20240105451-A1 SEMICONDUCTOR SUBSTRATE MANUFACTURING METHOD AND COMPOSITION JSR CORPORATION (JP) 2024-03-28 US disclosed
US-11935803-B2 Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer and semiconductor device MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-03-19 US disclosed
WO-2023199881-A1 METHOD FOR PRODUCING SEMICONDUCTOR SUBSTRATE AND RESIST UNDERLAYER FILM FORMING COMPOSITION JSR株式会社 2023-10-19 WO disclosed
CN-1419546-A 4, 5-dihydro-1H-pyrazole derivatives having CB 1-antagonistic activity SOLVAY PHARM BV (NL) 2003-05-21 CN disclosed
US-6476060-B2 DRUG ABUSE; PSYCHOLOGICAL DISORDERS; GASTROINTESTINAL DISORDERS; CARDIOVASCUALR DISORDERS SOLVAY PHARMACEUTICALS, B.V. (NL) 2002-11-05 US disclosed
EP-1206447-A1 SELECTIVE INHIBITORS OF THE UROKINASE PLASMINOGENE ACTIVATORS Wilex Biotechnology GmbH (DE) 2002-05-22 EP disclosed
US-20010053788-A1 4,5-dihydro-1H-pyrazole derivatives having CB1-antagonistic activity SOLVAY PHARMACEUTICALS B.V. 2001-12-20 US disclosed
WO-2001014324-A1 SELECTIVE INHIBITORS OF THE UROKINASE PLASMINOGENE ACTIVATORS WILEX AG (DE) 2001-03-01 WO disclosed
WO-2000078723-A1 PROCESS FOR THE PREPARATION OF BUTOXYCARBONYLIMINO COMPOUNDS AND INTERMEDIATES THEREFOR GLAXO GROUP LIMITED (GB) 2000-12-28 WO disclosed
EP-1037668-A1 TRANSFECTION PARTICLES Boehringer Ingelheim International GmbH (DE) 2000-09-27 EP disclosed
EP-0945138-A1 Transfection particles Université Louis Pasteur de Strasbourg (FR) 1999-09-29 EP disclosed
WO-1999037667-A1 EFFLUX PUMP INHIBITORS MICROCIDE PHARMACEUTICALS, INC. (US) 1999-07-29 WO disclosed
WO-1999029349-A1 TRANSFECTION PARTICLES BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 1999-06-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010053788-A1 4,5-dihydro-1H-pyrazole derivatives having CB1-antagonistic activity CNR1, CNR2, CBR3 NOS1 3155/4885ELANE 3992/4885CYP17A1 1171/4885
US-12415828-B2 Modified oligonucleotides and methods for their synthesis RNGTT, TYMP, POLM NOS1 4361/4885ELANE 2895/4885CYP17A1 4132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.