Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.80 |
| ▸ | LMNA | P02545 | 2/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.80 |
| ▸ | RAB9A | P51151 | 1/20 | 0.80 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.80 |
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.61 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fenbufen SCHEMBL11329267 | 0.89 | SMN1; SMN2 (1.00) | FFAR1SMN1; SMN2LMNACYP1A2RAB9A | |
| Fenbufen SCHEMBL25117 | 0.89 | SMN1; SMN2 (1.00) | FFAR1SMN1; SMN2LMNACYP1A2RAB9A | |
| Fenbufen SCHEMBL11393779 | 0.88 | SMN1; SMN2 (0.96) | FFAR1SMN1; SMN2LMNACYP1A2RAB9A | |
| Felbinac SCHEMBL28284677 | 0.86 | LMNA (0.95) | FFAR1SMN1; SMN2LMNACYP1A2RAB9A | |
| SCHEMBL10884944 | 0.84 | SMN1; SMN2 (0.88) | FFAR1SMN1; SMN2LMNACYP1A2RAB9A | |
| Felbinac SCHEMBL26084 | 0.84 | LMNA (1.00) | FFAR1LMNAGAAABCC4TSHR | |
| Felbinac SCHEMBL8844919 | 0.82 | LMNA (0.95) | FFAR1LMNAGAAABCC4TSHR | |
| Felbinac SCHEMBL384892 | 0.82 | LMNA (0.95) | FFAR1LMNAGAAABCC4TSHR | |
| Felbinac SCHEMBL28284672 | 0.82 | LMNA (0.95) | FFAR1LMNAGAAABCC4TSHR | |
| Felbinac SCHEMBL28286223 | 0.82 | LMNA (0.95) | FFAR1LMNAGAAABCC4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759750-A4 | COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES | SHAPIRO HOWARD K (US) | 1998-05-27 | — | — | EP | claimed |
| EP-0759750-A1 | COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES | SHAPIRO, Howard, K. (US) | 1997-03-05 | — | — | EP | claimed |
| WO-1995031194-A1 | COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES | SHAPIRO HOWARD K (US) | 1995-11-23 | — | — | WO | claimed |
| EP-0977725-A1 | NEW FATTY ACID DERIVATIVES | NORSK HYDRO ASA (NO) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998032718-A1 | NEW FATTY ACID DERIVATIVES | NORSK HYDRO ASA (NO) | 1998-07-30 | — | — | WO | disclosed |