SCHEMBL8199862

SCHEMBL8199862

CSCC[C@H](NC(=O)c1ccc(C=C(Cc2ncc(C)[nH]2)c2ccc(F)cc2)cc1-c1ccccc1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 13/20 0.51
FNTB P49356 13/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8207394 0.90 FNTA (0.39) FNTAFNTB
SCHEMBL8199776 0.89 FNTA (0.49) FNTAFNTB
SCHEMBL8205809 0.87 FNTA (0.46) FNTAFNTB
SCHEMBL8207254 0.86 FNTA (0.47) FNTAFNTB
SCHEMBL8206683 0.85 BRS3 (0.41)
SCHEMBL8199385 0.85 FNTA (0.52) FNTAFNTB
SCHEMBL8210056 0.83 SLC6A4 (0.40)
SCHEMBL7703436 0.82 FNTA (0.53) FNTAFNTB
SCHEMBL7703440 0.82 FNTA (0.53) FNTAFNTB
SCHEMBL8209424 0.82 FNTA (0.43) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975603-A1 INHIBITORS OF FARNESYL PROTEIN TRANSFERASE ZENECA LIMITED (GB) 2000-02-02 EP claimed
WO-1998032741-A1 INHIBITORS OF FARNESYL PROTEIN TRANSFERASE ZENECA LIMITED (GB) 1998-07-30 WO claimed
EP-0975603-A1 INHIBITORS OF FARNESYL PROTEIN TRANSFERASE ZENECA LIMITED (GB) 2000-02-02 EP disclosed
WO-1998032741-A1 INHIBITORS OF FARNESYL PROTEIN TRANSFERASE ZENECA LIMITED (GB) 1998-07-30 WO disclosed