Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 17/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | BAD | Q92934 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8210056 | 0.91 | SLC6A4 (0.40) | BRS3MEN1POLBKMT2A | |
| SCHEMBL8207394 | 0.85 | FNTA (0.39) | — | |
| SCHEMBL8199862 | 0.85 | FNTA (0.51) | — | |
| SCHEMBL8206480 | 0.82 | NR4A2 (0.37) | MEN1POLBKMT2A | |
| SCHEMBL8213603 | 0.79 | HTR2B (0.40) | BRS3 | |
| SCHEMBL8210100 | 0.76 | P4HB (0.38) | MEN1POLBKMT2A | |
| SCHEMBL7241309 | 0.76 | MEN1 (0.35) | LDHAMEN1POLBKMT2ABCL2L1 | |
| SCHEMBL7241306 | 0.76 | MEN1 (0.35) | LDHAMEN1POLBKMT2ABCL2L1 | |
| SCHEMBL8210369 | 0.74 | BRS3 (0.46) | BRS3 | |
| SCHEMBL8210054 | 0.73 | SLC6A4 (0.40) | BRS3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975603-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998032741-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 1998-07-30 | — | — | WO | disclosed |