Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.45 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anthracene SCHEMBL28302098 | 0.88 | IMPDH2 (0.53) | CA1CA2IMPDH2IMPDH1ALDH1A1 | |
| SCHEMBL27914677 | 0.88 | CA1 (0.43) | CA1CA2IMPDH2IMPDH1ALDH1A1 | |
| SCHEMBL5749182 | 0.88 | ALDH1A1 (0.44) | CA1CA2IMPDH2IMPDH1ALDH1A1 | |
| SCHEMBL11423777 | 0.88 | TSHR (0.47) | CA1CA2IMPDH2IMPDH1ALDH1A1 | |
| SCHEMBL21298083 | 0.85 | CA1 (0.52) | CA1CA2IMPDH2IMPDH1ALDH1A1 | |
| SCHEMBL21298078 | 0.85 | CA1 (0.52) | CA1CA2IMPDH2IMPDH1ALDH1A1 | |
| SCHEMBL31085570 | 0.84 | TSHR (0.44) | CA1CA2IMPDH2IMPDH1ALDH1A1 | |
| SCHEMBL31588139 | 0.84 | ALDH1A1 (0.42) | CA1CA2IMPDH2IMPDH1ALDH1A1 | |
| SCHEMBL29176694 | 0.84 | CYP11B1 (0.42) | CA1CA2IMPDH2IMPDH1ALDH1A1 | |
| SCHEMBL31050902 | 0.84 | CA1 (0.52) | CA1CA2IMPDH2IMPDH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016205405-A1 | COORDINATION POLYMER | NDSU RESEARCH FOUNDATION (US) | 2016-12-22 | — | — | WO | claimed |
| EP-2382241-B1 | POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS | BRIDGESTONE CORP (JP) | 2016-11-23 | — | — | EP | claimed |
| US-8785566-B2 | Polymers functionalized with polycyano compounds | BRIDGESTONE CORPORATION (JP) | 2014-07-22 | — | — | US | claimed |
| US-10081688-B2 | Polymers functionalized with polycyano compounds | BRIDGESTONE CORPORATION (JP) | 2018-09-25 | — | — | US | disclosed |
| US-20170002112-A1 | POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2017-01-05 | — | — | US | disclosed |
| WO-2016205405-A1 | COORDINATION POLYMER | NDSU RESEARCH FOUNDATION (US) | 2016-12-22 | — | — | WO | disclosed |
| EP-2382241-B1 | POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS | BRIDGESTONE CORP (JP) | 2016-11-23 | — | — | EP | disclosed |
| US-9447213-B2 | Polymers functionalized with polycyano compounds | BRIDGESTONE CORPORATION (JP) | 2016-09-20 | — | — | US | disclosed |
| US-20140275403-A1 | POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2014-09-18 | — | — | US | disclosed |
| US-8785566-B2 | Polymers functionalized with polycyano compounds | BRIDGESTONE CORPORATION (JP) | 2014-07-22 | — | — | US | disclosed |
| CN-102361888-A | Polymers functionalized with polycyano compounds | BRIDGESTONE CORP | 2012-02-22 | — | — | CN | disclosed |
| US-20110288200-A1 | POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2011-11-24 | — | — | US | disclosed |
| EP-2382241-A2 | POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS | Bridgestone Corporation (JP) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010085631-A2 | POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2010-07-29 | — | — | WO | disclosed |
| US-4249022-A | Process for the manufacture of 1,4-disubstituted bicyclic or tricyclic compounds and new 1,4-disubstituted bicyclic compounds | CIBA-GEIGY CORPORATION (US) | 1981-02-03 | — | — | US | disclosed |
| US-4154754-A | 1,4-Dicyanonaphthalenes | CIBA-GEIGY CORPORATION (US) | 1979-05-15 | — | — | US | disclosed |
| US-4048212-A | Process for the manufacture of 1,4-dicyanonaphthalenes | CIBA-GEIGY CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-4011261-A | PROCESS FOR THE MANUFACTURE OF 1,4-DISUBSTITUTED BICYCLIC OR TRICYCLIC COMPOUNDS AND NEW 1,4-DISUBSTITUTED BICYCLIC COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1977-03-08 | — | — | US | disclosed |