Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200327 | 0.92 | KMT2A (0.52) | PKMHPGDPOLBMAPTGAA | |
| SCHEMBL8200143 | 0.91 | PKM (0.52) | PKMHPGDPOLBMAPTKMT2A | |
| SCHEMBL8211919 | 0.90 | KDM4E (0.54) | PKMHPGDPOLBMAPTGAA | |
| Bicarbonate SCHEMBL7890878 | 0.89 | POLB (0.51) | PKMHPGDPOLBMAPTGAA | |
| SCHEMBL8206662 | 0.85 | GAA (0.53) | PKMPOLBMAPTGAAHIF1A | |
| SCHEMBL8212994 | 0.85 | POLB (0.54) | POLBMAPTGAAHIF1AKMT2A | |
| SCHEMBL8212725 | 0.85 | GAA (0.56) | PKMHPGDPOLBMAPTGAA | |
| SCHEMBL8199034 | 0.83 | GAA (0.50) | PKMHPGDPOLBMAPTGAA | |
| SCHEMBL8200394 | 0.82 | HPGD (0.55) | PKMHPGDPOLBMAPTKMT2A | |
| SCHEMBL7881605 | 0.82 | MAPT (0.52) | PKMHPGDMAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |