Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL7890878 | 0.92 | POLB (0.51) | KMT2AMAPTPOLBGAAHIF1A | |
| SCHEMBL8200015 | 0.92 | PKM (0.52) | KMT2AMAPTPOLBGAAHIF1A | |
| SCHEMBL7881605 | 0.90 | MAPT (0.52) | KMT2AMAPTKDM4ELMNAHPGD | |
| SCHEMBL8206933 | 0.88 | LMNA (0.57) | KMT2AMAPTPOLBGAAKDM4E | |
| SCHEMBL8220300 | 0.88 | MAPT (0.48) | KMT2AMAPTPOLBKDM4ELMNA | |
| SCHEMBL8212952 | 0.86 | GAA (0.55) | KMT2AMAPTPOLBGAAHIF1A | |
| SCHEMBL7420721 | 0.85 | POLB (0.53) | KMT2AMAPTPOLBGAAHIF1A | |
| SCHEMBL7888442 | 0.84 | POLB (0.52) | KMT2AMAPTPOLBGAAHIF1A | |
| SCHEMBL8200143 | 0.83 | PKM (0.52) | KMT2AMAPTPOLBKDM4ELMNA | |
| SCHEMBL7424975 | 0.83 | GAA (0.50) | KMT2AMAPTPOLBGAAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |