SCHEMBL8200192

SCHEMBL8200192

[CH2]Oc1cc(OC)c(CN)c(OC)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.38
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
TAAR1 Q96RJ0 3/20 0.35
ADRA1A P35348 2/20 0.35
KEAP1 Q14145 1/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
HTR2B P41595 1/20 0.34
AOC3 Q16853 1/20 0.34
PTPN1 P18031 1/20 0.34
CD274 Q9NZQ7 3/20 0.34
ADRA2A P08913 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL442070 0.85 CYP1A2 (0.50) CYP1A2CA12CA1CA2CA7
Hydrochloric Acid SCHEMBL1093815 0.83 CYP1A2 (0.48) CYP1A2CA12CA1CA2CA7
SCHEMBL16437141 0.76 CYP1A2 (0.36) CYP1A2CA12CA1CA2CA7
SCHEMBL23861312 0.76 GAA (0.47) ALDH1A1CYP3A4TAAR1KEAP1HTR2A
SCHEMBL12776535 0.76 ACHE (0.52) ALDH1A1CYP3A4TAAR1KEAP1HTR2A
SCHEMBL27649220 0.75 CYP1A2 (0.35) CYP1A2CA12CA1CA2CA7
SCHEMBL28756671 0.74 PTPN1 (0.44) CYP1A2CA12CA1CA2CA7
SCHEMBL2001235 0.74 CYP3A4 (0.54) CYP1A2CYP3A4TAAR1PTPN1
SCHEMBL13828731 0.73 CYP1A2 (0.44) CYP1A2CA12CA1CA2CA7
SCHEMBL20763776 0.73 ADRA2A (0.40) CYP1A2ADRA1AADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6127339-A AND REMOVING IT FROM A BODY FLUID; ABSORBENT COMPRISING A PEPTIDE OF AMINO ACID SEQUENCE WHICH INCLUDES PHENYLALANINE OR TRYPTOPHAN AND ARGININE OR LYSINE, HAS SPECIFIED ELECTRICAL CHARGE, AND IS BONDED TO A WATER INSOLUBLE CARRIER ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2000-10-03 US disclosed
EP-0838472-A1 PEPTIDES BINDING TO LOW-DENSITY LIPOPROTEINS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1998-04-29 EP disclosed