Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205106 | 0.78 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2C19 | |
| SCHEMBL27578792 | 0.76 | DPP4 (0.42) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2C19 | |
| SCHEMBL27817928 | 0.76 | CHRNA7 (0.34) | SLC6A2SLC6A4SLC6A3MAPTMAPK13 | |
| SCHEMBL30975300 | 0.71 | CPB2 (0.47) | CYP2C19CYP19A1 | |
| SCHEMBL25152964 | 0.68 | GABBR2 (0.41) | CYP3A4CYP2C19CYP19A1 | |
| SCHEMBL25152277 | 0.68 | GABBR2 (0.41) | CYP3A4CYP2C19CYP19A1 | |
| SCHEMBL5495226 | 0.68 | SLC6A4 (0.50) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2C19 | |
| SCHEMBL5843905 | 0.68 | SLC6A4 (0.38) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2C19 | |
| SCHEMBL5843901 | 0.68 | SLC6A4 (0.38) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2C19 | |
| SCHEMBL5842929 | 0.68 | SLC6A4 (0.38) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043227-A | C11 carbamates of macrolide antibacterials | PFIZER INC. (US) | 2000-03-28 | — | — | US | disclosed |